Manufacturer: Abbott
Salt Composition : Levetiracetam(1000mg)
Strip of 10 Tablet
(Inclusive of all taxes)
LEVESAM 1GM TABLET is also used in combination with other antiepileptic medicines to treat partial onset seizures with or without generalisation (abnormal activity involving one side of the brain), myoclonic seizures (short, shock-like jerks of a muscle or involving group of muscles), juvenile myoclonic epilepsy (myoclonic seizures in adolescents from 12 years of age), primary generalised tonic-clonic seizures (major fits which includes loss of consciousness), and idiopathic generalised epilepsy (type of epilepsy which is thought to have a genetic cause).
Along with the treatment with LEVESAM 1GM TABLET, your doctor may suggest you make some lifestyle changes such as healthy eating and sleeping habits, managing stress, and exercising or meditating regularly. Prior to starting the treatment with LEVESAM 1GM TABLET, your doctor might ask you to take some diagnostic tests.
Before taking LEVESAM 1GM TABLET inform your doctor if you have liver, kidney or heart diseases. LEVESAM 1GM TABLET should be used with caution in pregnant women and not recommended for use in breast-feeding women.
LEVESAM 1GM TABLET is not recommended for use in children and adolescents below 16 years of age, however it can be used in combination with other medicines. Consult with your doctor before taking. Some of the serious side effects of LEVESAM 1GM TABLET includes thoughts of self-harming, contact your doctor immediately if you notice symptoms of depression or suicidal thoughts.
The most common side effects of taking LEVESAM 1GM TABLET are inflammation of nose and throat, sleepiness, dizziness, lethargy, anorexia, depression, anxiety, vertigo, cough, nausea. Contact your doctor if you experience these above side effects or worsen.
LEVESAM 1GM TABLET acts on the brain and modify the release of certain nerve chemicals. Brain cells communicate with each other using electrical signals and chemicals. When there is any disturbance in this communication, seizure (fits) happens. Levetiracetam combines with a protein (SV2A) present in central nervous system and inhibits the release of abnormal nerve chemicals (neurotransmitters). This does not affect the normal brain communication.
Food does not affect the extent of absorption of levetiracetam but it decreases Cmax by 20% and delays Tmax by 1.5 hours. The pharmacokinetics of levetiracetam are linear over the dose range of 500 5000 mg. Steady state is achieved after 2 days of multiple twice-daily dosing.
SIDE EFFECTS OF LEVESAM 1GM TABLET
COMMON
Inflammation of nose and throat (nasopharyngitis)
Somnolence (excessive sleepiness)
Headache
Loss of appetite
Depression, aggression, anxiety
Insomnia, nervousness, irritability
Convulsion, balance disorder
Dizziness
Lethargy, tiredness
Tremor (involuntary trembling)
Vertigo (sensation of rotation or spinning)
Cough
Abdominal pain
Diarrhoea, indigestion
Vomiting, nausea
Rash
UNCOMMON
Decreased number of blood platelets (easy bruising, more bleeding, bleeding from gums or nose)
Decreased number of white blood cells (chills, fever, body ache, headache)
Weight decrease or increase
Panic attack, emotional instability, mood swings
Loss of memory, forgetfulness, abnormal or impaired coordination
Paraesthesia (tingling)
Disturbance in attention (loss of concentration)
Double vision, vision blurred
Hair loss, eczema
Muscle weakness, muscle pain
RARE
Infection
Decreased blood sodium concentration
Delirium
Seizures may become worse or happen frequently
Uncontrollable muscle spasms affecting the head, body and limbs
Difficulty in controlling movements, hyperactivity
Change of the heart rhythm (Electrocardiogram)
Pancreatitis
Liver failure, hepatitis (abdominal pain, dark urine, itching, light coloured stools, jaundice, swelling of the abdomen)
Rhabdomyolysis (breakdown of muscle tissue)
Limp or difficulty in walking
Fever, unstable blood pressure and heart rate, muscle stiffness, low level of consciousness, confusion (signs of a disorder called neuroleptic malignant syndrome)
Stop taking LEVESAM 1GM TABLET and inform your doctor immediately if you experience any of the following side effects:
Signs of anaphylactic reaction (weakness, light-headedness, dizziness or have difficulty breathing)
Signs of Quincke’s oedema (swelling of the face, lips, tongue and throat)
Signs of Drug Reaction with Eosinophilia and Systemic Symptoms (flu-like symptoms, rash on the face followed by an extended rash with a high temperature, enlarged lymph nodes)
Signs of sudden decrease of kidney function (low urine volume, tiredness, nausea, vomiting, confusion and swelling in the legs, ankles or feet)
Signs of erythema multiforme (skin rash which may form blisters and look like small targets like central dark spots surrounded by a paler area, with a dark ring around the edge)
Signs of Stevens-Johnson syndrome (widespread rash particularly around the mouth, nose, eyes and genitals, with blisters and peeling skin)
Signs of toxic epidermal necrolysis (severe form of rash causing skin peeling in more than 30% of the body surface)
Signs of serious mental changes that can be symptoms of encephalopathy (confusion, sleepiness, loss of memory, forgetfulness, abnormal behaviour, involuntary or uncontrolled movements)
Abnormal thoughts, feeling irritable or reacting more aggressively
Aggravation (worsening) of epilepsy
contraindicated in patients with a hypersensitivity to levetiracetam. Reactions have included anaphylaxis and angioedema [see Warnings and Precautions (5.3)]. If you provide additional keywords, you may be able to browse through our database of Scientific Response Documents.
LEVESAM 1GM TABLET should be used with caution in pregnant women only if considered clearly necessary by the doctor. Consult your doctor before taking LEVESAM 1GM TABLET.
Avoid the consumption of alcohol while taking LEVESAM 1GM TABLET.
LEVESAM 1GM TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.
Levetiracetam is indicated as an adjunctive therapy in the treatment of partial onset seizures in epileptic patients who are one month of age and older.
Drug-Drug Interaction: This medicine may have interaction with antianxiety or antiepileptic medicines (carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone), anti-HIV drugs (amprenavir, ritonavir), acidity medicine (cimetidine), drugs to treat chronic alcoholism (disulfiram), anti-tuberculosis drug (rifampicin), anti-Parkinson’s drug (levodopa), and asthma drugs (theophylline).
Drug-Food Interaction: LEVETIRACETAM may interact with a multivitamin, multi-mineral, or other herbal supplements. So, if you are using any of the OTC items, please tell your doctor.
Drug-Disease Interaction: Effectiveness of LEVETIRACETAM is affected in haemodialysis (when kidneys are not naturally able to perform a function), anaemia (low haemoglobin level). Also, obese people (with a BMI greater than 25) should consult a doctor before taking LEVETIRACETAM.
Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Keep LEVESAM 1GM TABLET out of reach of children
Store at room temperature below 25°C
If you or anyone else accidentally took extra dose of LEVESAM 1GM TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage of LEVESAM 1GM TABLET are sleepiness, aggression, agitation, inhibition of breathing, decrease of alertness and coma.
Take LEVESAM 1GM TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
What is LEVESAM 1GM TABLET and why is it prescribed?
LEVESAM 1GM TABLET contains Levetiracetam which belongs to the group of medicines called Anticonvulsants. It is used in the treatment of epilepsy and also used in combination with other antiepileptic medicines to treat partial onset seizures with or without generalisation, myoclonic seizures, juvenile myoclonic epilepsy, primary generalised tonic-clonic seizures and idiopathic generalised epilepsy.
Can I stop taking LEVESAM 1GM TABLET if I start to feel better?
You must keep taking LEVESAM 1GM TABLET for the time your doctor has prescribed it to you. Stopping suddenly may cause increase in seizures. If you wish to discontinue taking LEVESAM 1GM TABLET, ask for your doctor’s advice to avoid the chances of increase in seizures.
What is the best time to take LEVESAM 1GM TABLET?
Always take LEVESAM 1GM TABLET as advised by your doctor. Consult your doctor for advice before taking the medicine.
How to manage if I miss a dose of LEVESAM 1GM TABLET?
If you miss one or two doses of LEVESAM 1GM TABLET, you should contact your doctor. Do not take a double dose to make up for the missed dose of LEVESAM 1GM TABLET.
