Livial 2.5mg Tablet (28'S)

Manufacturer: Organon (India) Ltd

Salt Composition : Tibolone(2.5mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Livial Tablet can be taken with or without food, but better to take it at a fixed time each day for better efficacy. It should be swallowed whole with water. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.


The most common side effects of this medicine are lower abdominal pain, abnormal hair growth, endometrial hyperplasia, vaginal discharge, breast tenderness, genital itching, vaginal bleeding, pelvic pain, cervical thickening,  and weight gain. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs. If you experience any such effects, consult your doctor.


Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.


Basic Information

Mechanism Of Action

Livial Tablet is a hormonal medication. It has effects similar to estrogen, progesterone and androgen. It substitutes for the loss of estrogen production in postmenopausal women and treats menopausal symptoms such as hot flashes, night sweats and vaginal problems. It also prevents bone loss following menopause.

Pharmacokinets

The mean oral bioavailability of tibolone is 92%. Its plasma protein binding is 96.3%. It is bound to albumin, and both tibolone and its metabolites have low affinity for SHBG. Tibolone is metabolized in the liver and intestines.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Livial

Breast pain

Vaginal bleeding

Weight gain

Abnormal hair growth

Breast tenderness

Cervical thickening

Endometrial hyperplasia

Genital itching

Lower abdominal pain

Pelvic pain

Vaginal discharge

Contra Indications

Women with any history of blood clotting (arterial thromboembolic) disease including stroke, transient ischemic attack, myocardial infarction and angina, breast cancer.

Allergic to this medicine.

History of liver disease with abnormal liver enzymes.

Any vaginal bleeding.

Pregnancy Related Information

Livial Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Product And Alcohol Interaction

It is unsafe to consume alcohol with Livial Tablet.

Breast Feeding Related Information

Information regarding the use of Livial Tablet during breastfeeding is not available. Please consult your doctor.

Indications

Tibolone substitutes for the loss of oestrogen production in postmenopausal women and alleviates menopausal symptoms. Tibolone prevents bone loss following menopause or ovariectomy. Clinical trial information of Tibolone: Relief of oestrogen-deficiency symptoms.

Interactions

Drug-Drug Interaction: TIBOLONE may interact with a blood thinner (warfarin), anticonvulsants (phenytoin, carbamazepine, phenobarbital), and antitubercular drugs (rifampicin).

Drug-Food Interaction: TIBOLONE may interact with St. John’s wort (herbal medicine to treat depression).

Drug-Disease Interaction: If you have high blood pressure, gallstones, diabetes, migraine, epilepsy (fits), asthma, fluid retention due to kidney or heart problems, unexplained vaginal bleeding, breast cancer, liver disease, systemic lupus erythematosus (an autoimmune disease), estrogen-sensitive cancer, porphyria, fibroids in the womb, endometrial hyperplasia (excessive thickening of the womb lining), blood clotting disorder or blood clot in the vein, inform your doctor before taking TIBOLONE.

Drug-Drug Interactions Checker List:

WARFARIN

PHENYTOIN

CARBAMAZEPINE

PHENOBARBITAL

RIFAMPICIN

Typical Dosage

Do not chew, crush or break it. Livial Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Livial Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.

It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.

Take it at the same time everyday to help you remember to take it.

It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Stop taking Livial Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.

Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.

Do not use Livial Tablet if you have a history of blood clots and liver disease. 

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Livial Tablet may be taken with or without food, but it is better to take it at a fixed time.

FAQs

Q. Does Livial Tablet contain progesterone?

It is a synthetic medicine which is used to fulfill the functions of the normal sex hormones like estrogen and progesterone in the body of women. On taking Livial Tablet it is broken down in our body and functions like estrogen, progesterone and a part to testosterone (male sex hormone). It is prescribed to compensate for the loss of estrogen production in postmenopausal women and decrease the menopausal symptoms.

Q. Is Livial Tablet a combined HRT?

Yes, Livial Tablet is a type of medicine used in hormone replacement therapy (HRT) which is given to post-menopausal women. It is given to prevent the adverse effects on various organs and systems due to decrease in the levels of hormones like estrogen and progesterone. It shows positive effect on different tissues in the body, such as brain, vagina, and bones.

Q. Can Livial Tablet be taken during pregnancy?

No, Livial Tablet is not to be taken in pregnancy or if you are planning to get pregnant. In case you become pregnant during treatment with this medication you should contact your doctor and the medicine should be withdrawn immediately.

Q. Does Livial Tablet help in elevating mood?

Yes, this medicine has shown positive results when given to postmenapausal women as a substitute for the hormonal deprivation. Patients have experienced reduction in the menopausal complaints like persistent fatigue, blunted motivation, and loss of sexual desire. However, consult the doctor regarding any query for your mood problems before you start taking this medication.