Manufacturer: Samarth Life Sciences Pvt Ltd
Salt Composition : Labetalol(100mg)
It is also used in certain conditions to lower high blood pressure after chest pain or while using anaesthetics that lower blood pressure during surgery. The main component of this injection is Labetalol. It is a beta-blocker. The mode of action of Lobet 100 mg injection is to lower blood pressure and relax blood vessels. It increases the blood flow to the heart and slows down the heart rate. It can also reduce heart rate while maintaining normal cardiac output. Dizziness, drowsiness, headache, and a feeling of tightness around the skull are some of the common side effects of Lobet 100 mg injection. Follow your doctor’s directions for using Lobet 100 mg injection. It must be given by a doctor or a healthcare professional in the hospital or a clinical setting. Notify your doctor if you have a history of severe heart conditions; this injection should not be given in such cases. This injection is also not indicated if the heart rate is around 45 to 50 beats per second. Inform your doctor before taking this medicine if you are pregnant or breastfeeding.
Lobet 100 mg injection is composed of Labetalol. It is a beta-blocker class of medicine. It works by blocking two different types of receptors: alpha and beta. Hence, it has a dual mode of action. By blocking these receptors, it prevents the action of various chemical messengers such as dopamine, norepinephrine, and epinephrine. This results in relaxing the muscles of the heart and blood vessels, improving blood flow, slowing heart rate, and lowering blood pressure.
Labetalol HCl is completely absorbed from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The relative bioavailability of labetalol HCl tablets compared to an oral solution is 100%.
Dizziness or lightheadedness
Tingling scalp or skin
Excessive tiredness
Headache
Upset stomach
Stuffy nose
If you have a history of serious hypersensitivity to Labetalol or similar medications. Serious allergic reactions require immediate emergency treatment with supportive measures.
If you have uncontrolled and refractory heart failure
If you have a low heart rate or Bradycardia (less than 45 -50 beats per minute).
If you have a condition known as sick sinus syndrome, a type of heart block, and second or third-degree heart block.
If you are diagnosed with decompensated cardiac insufficiency.
If you have a history of severe breathing problems such as asthma.
If you have low blood pressure.
If you have untreated pheochromocytoma (tumour on adrenal glands).
If you have metabolic acidosis.
If you have low cardiac output. This injection should not be given to lower blood pressure after an acute heart attack or myocardial infarction.
No, Lobet injection can be unsafe for pregnant women, especially if used in the second and third trimesters. It should be only used if the medicine's benefits outweigh the potential risk. A few studies have shown that it can cause low blood pressure, low heart rate, low blood sugar, etc., in the foetus. However, in some cases, doctors may prescribe it to lower high blood pressure during pregnancy when fast control of blood pressure is necessary.
Drinking alcohol while you are taking a Lobet injection is not recommended. Alcohol will increase the effects of this injection, leading to low blood pressure. It also causes side effects such as sleepiness and dizziness.
A few studies have shown that only low levels of this medicine pass into the breastmilk and would not be expected to cause any side effects in breastfed infants. No special care is needed in most infants. The Lobet injection should be given only if your doctor prescribes it.
The FDA-approved indication for labetalol is to treat arterial hypertension, which ranges from acute hypertensive crises (urgent/emergency) to stable chronic hypertension.
Drug-Drug Interaction: LABETALOL may interact with a painkiller (aspirin, indomethacin, ibuprofen), diuretic (furosemide), anti-hypertensive (amlodipine, verapamil, clonidine), hormone (levothyroxine), cardiac glycoside (digoxin), anti-arrhythmic (amiodarone), anti-depressants (imipramine), anti-diabetic (metformin, glimepiride, acarbose, repaglinide, insulin), anti-migraine (ergotamine, dihydroergotamine), anti-Alzheimer (donepezil, galantamine, rivastigmine) anti-psychotic (chlorpromazine)
Drug-Food Interaction: No interactions found/established.
Drug-Disease Interaction: Inform your doctor if you have congestive heart failure (heart problems), hemodialysis, bradyarrhythmia, diabetes, ischemic heart disease, asthma/COPD, glaucoma, hyperlipidemia, hyperthyroidism, myasthenia gravis (muscle problems), psoriasis, Prinzmetal angina, liver diseases or kidney dysfunction.
Drug-Drug Interactions Checker List:
ASPIRIN
IBUPROFEN
INDOMETHACIN
FUROSEMIDE
AMLODIPINE
VERAMAPIL
CLONIDINE
LEVOTHYROXINE
DIGOXIN
AMIDODARONE
IMIPRAMINE
METFORMIN
GLIMEPIRIDE
ACARBOSE
REPAGLINIDE
INSULIN
ERGOTAMINE
DIHYDROERGOTAMINE
DONEPEZIL
GALANTAMINE
RIVASTIGMINE
CHLORPROMAZINE
Do not take this injection by yourself.
Do not stop this injection in the middle of the treatment.
Store Lobet injection below 30 degrees celsius. Do not let the medicine freeze. Store them in their original container to keep them away from direct sunlight. Keep Lobet 100 mg injection away from pets and children. Dispose of the packaging carefully after use. Do not use the medicine if the package has been opened. Check the expiration date on the packaging before taking the injection. If the medicine is past the expiration date, do not use it. Dispose of unused/expired medicine as biomedical waste.
Lobet 100 mg injection is given at a hospital by the doctor or healthcare professional. They will monitor the dose of Lobet 100 mg injection during the whole injection period. It is unlikely that the dose will be missed in this situation. If you think the doctor might have missed a dose, inform them.
Overdose symptoms due to an excess of Lobet 100 mg injection can include adverse effects such as chest pain or discomfort, lightheadedness, dizziness, or fainting, slow or irregular heartbeat, and unusual tiredness or weakness. If you notice any such symptoms due to an overdose of Lobet 100 mg injection, inform your doctor immediately and seek medical treatment.
You have an electrolyte imbalance. Appropriate steps should be taken to restore or maintain it.
You are noticing any skin rashes or dry eyes.
You are planning to have cataract surgery and are using this injection.
You have severe liver damage or injury, and if you have jaundice (yellowing of skin and eyes)
You have any known heart condition.
You have a blockage in the arteries of the heart.
You are planning to have any surgery or dental procedure, and anaesthetic medicines are used during those procedures.
You have blood circulation disorders such as Raynaud’s syndrome (low blood flow to fingers and toes).
Your pulse rate is either falling or fluctuating.
You have any conditions that cause breathing problems or wheezing.
You have kidney insufficiency (low blood flow to the kidneys).
You are diagnosed with psoriasis, a skin condition.
Lobet 100 mg injection is given to the patient in the hospital by a doctor or healthcare professional.
Do not take this injection by yourself.
Do not stop this injection in the middle of the treatment.
Lobet injection is given intravenously (injected directly into the veins).
This injection is given as an infusion mixed with normal saline or dextrose.
Follow the instructions given by the doctor for injecting and aftercare.
If you are having any breathing problems, rash, or swelling, inform your doctor immediately.
Q: Can I use Lobet 100 mg injection before having cataract surgery?
A: Lobet injection can affect pupils during cataract surgery, so let your surgeon know before the cataract procedure. It will help the doctor manage the complications in advance which could occur during the surgery. Also, inform your surgeon of Lobet injection use before any medical procedure that requires general anaesthesia, as this injection might mask the effects of sudden blood loss.
Q: Can Lobet injection cause sudden low blood pressure?
A: Postural hypotension (sudden fall in blood pressure after standing) and dizziness are some of the side effects of Lobet injection. Try not to stand up suddenly or start walking; instead, lie down or get up slowly. Regular monitoring of blood pressure is needed.
Q: Does Lobet injection cause any sexual dysfunction if I use it regularly?
A: Lobet injection may cause erectile dysfunction (impotence) or problems with ejaculation problems. Please consult your doctor if you have any concerns or notice such side effects.
