Lomtin 40mg Capsule (5'S)

Manufacturer: Dr Reddy's Laboratories Ltd

Salt Composition : Lomustine(40mg)


Lomtin 40mg Capsule should be taken on an empty stomach, but try to take it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.


The most common side effect of this medicine is decreased white blood cell count in your body. It may also cause nausea, vomiting, hair loss, and other side effects. Regular blood tests are required to check your blood cells along with kidney, liver, and heart function during treatment with this medicine. Inform your doctor if you observe signs of infections such as fever, chills, body ache, or if you have unusual bruising or bleeding.


Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Basic Information

Mechanism Of Action

Lomtin 40mg Capsule is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Pharmacokinets

CCNU is a nitrosourea alkylating agent. After oral or intravenous administration, CCNU is rapidly broken down to various intermediates by hepatic microsomal metabolic transformation. Following oral administration, little or no parent drug is detectable in plasma.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lomtin

Decreased white blood cell count

Nausea

Vomiting

Hair loss

Contra Indications

Adenovirus vaccine, live, BCG live intravesical, Influenza nasal vaccine live, Measles/mumps/rubella vaccine live, Rotavirus vaccine live, Smallpox vaccine (live vaccinia virus), Typhoid vaccine live, Varicella vaccine live, Yellow fever vaccine live, Zoster vaccine live.

Pregnancy Related Information

Lomtin 40mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product And Alcohol Interaction

It is unsafe to consume alcohol with Lomtin 40mg Capsule.

Breast Feeding Related Information

Information regarding the use of Lomtin 40mg Capsule during breastfeeding is not available. Please consult your doctor.

Indications

Lomustine is used to treat certain types of brain tumors. Lomustine is also used with other medications to treat Hodgkin's lymphoma (Hodgkin's disease) that has not improved or that has worsened after treatment with other medications. Lomustine is in a class of medications called alkylating agents.

Interactions

Drug-Drug Interactions: LOMUSTINE may interact with live vaccines, monoclonal antibodies (certolizumab, baricitinib, adalimumab ), antifungal drugs (ketoconazole), antipsychotic drug (clozapine), antirheumatic drug (leflunomide), etc.

Drug-Food Interactions: Avoid alcohol consumption and smoking.

Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease and pulmonary disorders before taking LOMUSTINE.

Drug-Drug Interactions Checker List:

CHOLERA VACCINE

TYPHOID VACCINE

ZIDOVUDINE

ABACAVIR

Typical Dosage

Lomtin 40mg Capsule is to be taken empty stomach.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Lomtin 40mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Lomtin 40mg Capsule should be taken on an empty stomach, but try to have it the same time every day.

Do not skip any dose and complete the course as suggested by your doctor.

Use an effective method of birth control to avoid pregnancy while taking this medication.

Your doctor may get regular blood tests done to monitor your blood cell count (CBC) and liver function.

Inform your doctor if you experience fever, chills, unusual bleeding and dark or bloody stools.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Lomtin 40mg Capsule is to be taken empty stomach.

FAQs

Q. Is Lomtin 40mg Capsule effective?

Lomtin 40mg Capsule is effective if taken as per the dose and for the duration prescribed by a doctor. It may be used in combination with other drugs/radiotherapy or surgery to get best results. Follow your doctor's instructions about this treatment carefully.

Q. How fast does Lomtin 40mg Capsule work?

Lomtin 40mg Capsule treatment includes administration of medicine in several sessions/cycles. Each cycle of Lomtin 40mg Capsule is usually a single oral dose given every 6-8 weeks. Duration of treatment may depend upon the type of cancer and body's response to the medicine. Total treatment with Lomtin 40mg Capsule may run over a few months.

Q. How long does Lomtin 40mg Capsule stay in the body?

Lomtin 40mg Capsule may stay in body from 16 hours to 2 days.