Lorazen Injection (2ml)

Manufacturer: Zenith Healthcare Ltd

Salt Composition : Lorazepam(2mg)

₹14.90

Vial of 2ml Injection

(Inclusive of all taxes)


Lorazen Injection may also be used to induce anesthesia before an investigation or a surgical procedure. It relieves anxiety and muscle tension, thus making the person comfortable before the operation or investigation procedure. This medicine is given as an injection under the supervision of a healthcare professional. Lorazen Injection may be given into your vein (intravenously) or into one of your muscles (intramuscularly). The recommended dose depends on your age, weight and why it is being used for you. It is usually used for a short-term only owing to its high habit-forming potential.


Side effects of this medicine include drowsiness, sedation, tiredness, confusion, depression, muscle weakness. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.


Basic Information

Mechanism Of Action

Lorazen Injection is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Pharmacokinets

lorazepam is well absorbed after oral administration. Peak concentrations are attained two hours following oral administration. The bioavailability of lorazepam is approximately 90%. Lorazepam crosses the blood/brain barrier freely by passive diffusion.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lorazen

Dizziness

Sedation

Injection site pain

Fatigue

Muscle weakness

Drowsiness

Contra Indications

(lorazepam) is contraindicated in patients with – hypersensitivity to benzodiazepines or to any components of the formulation. – acute narrow-angle glaucoma. Concomitant use of benzodiazepines, including Ativan, and opioids may result in profound sedation, respiratory depression, coma, and death.

Pregnancy Related Information

Lorazen Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product And Alcohol Interaction

It is unsafe to consume alcohol with Lorazen Injection.

Breast Feeding Related Information

Lorazen Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Lorazen Injection should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Lorazen Injection should be gradual.

Interactions

Drug-Drug Interactions: LORAZEPAM may interact with antianxiety or antiepileptic medicines (carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone), anti-HIV drugs (amprenavir, ritonavir), acidity medicine (cimetidine), medicines used to treat chronic alcoholism (disulfiram), anti TB drug (rifampicin), anti-Parkinson’s drug (levodopa), asthma drugs (theophylline), and antidepressants.

Drug-Food Interactions: Grapefruit, grapefruit juice and caffeine-containing food or drinks should be avoided as they can affect the working of LORAZEPAM.

Drug-Disease Interactions: Inform your doctor if you have acute alcohol intoxication, closed-angle glaucoma, drug dependence, renal/liver disease, respiratory depression, seizures, prolonged hypotension, prematurity, depression, obesity, paradoxical reactions and upper gastrointestinal disease.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.

Effects Of Missed Dosage

If you miss a dose of Lorazen Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor

It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.

Avoid consuming alcohol as it may increase dizziness and drowsiness.

Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. Is Lorazen Injection an opioid? Is it a habit-forming medicine?

No, Lorazen Injection is not an opioid. It belongs to the benzodiazepine group of medicines and is used for short-term treatment (2-4 weeks) only. It is a habit-forming medicine and can make a person physically and psychologically dependent.

Q. For how long will Lorazen Injection stay in my system?

Lorazen Injection may take around 3 days to get completely removed from the system.

Q. Are there any symptoms that I would experience if I get addicted to Lorazen Injection?

The most important symptom of addiction is that you may feel unpleasant if you do not take Lorazen Injection. Another symptom could be that you may increase the dose on your own to feel its effect.

Q. If I suddenly stop taking Lorazen Injection, will it affect me adversely?

You should reduce the dose of Lorazen Injection gradually before completely stopping it. Suddenly stopping it may lead to withdrawal symptoms which include loss of the sense of reality, feeling detached from life, and unable to feel emotion. Some patients have also experienced numbness or tingling in the arms or legs, tinnitus (ringing sounds in the ears), uncontrolled or overactive movements, twitching, shaking, feeling sick, being sick, stomach upsets or stomach pain, loss of appetite, agitation and abnormally fast heart beats. It can also cause panic attacks, dizziness or feeling faint, memory loss, hallucinations, feeling stiff and unable to move easily, feeling very warm, convulsions (sudden uncontrolled shaking or jerking of the body) and oversensitivity to light, sound and touch.