Lucentis 0.5mg Injection

Manufacturer: Novartis India Ltd

Salt Composition : Ranibizumab(0.5mg)


Lucentis Injection is administered directly into the eyeball by an eye specialist. You should not self administer this medicine at home. The common side effects include conjunctival hemorrhage, eye pain, eye floaters, increased intraocular pressure, and eye inflammation.


However, if you experience these side effects for a longer duration or any other symptoms which you think may be due to this medicine, please inform your doctor. It is not advised to drive after administration of this injection as it may cause blurring of vision.


Basic Information

Mechanism Of Action

Lucentis Injection is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the growth and leakage of abnormal blood vessels in the eye(s) that may cause vision loss.


Pharmacokinets

Ranibizumab binds to the receptor-binding site on VEGF-A, which inhibits the binding of VEGF molecules to their receptors on the surface of endothelial cells. 3,6 Ranibizumab blocks all isoforms of VEGF-A.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lucentis

Conjunctival hemorrhage

Eye pain

Increased intraocular pressure

Foreign body sensation in eyes

Blurred vision

Nausea

Dry eye

Eye itching

Cataract

Vitreous floaters

Vitreous detachment

Intraocular inflammation

Eye irritation

Increased lacrimation

Eyelid inflammation

Ocular hyperemia

Retinal disorder

Maculopathy

Eye discomfort

Posterior capsule opacification

Injection site hemorrhage

Nasopharyngitis (inflammation of the throat and nasal passages)

Anemia (low number of red blood cells)

Joint pain

Renal failure

Peripheral neuropathy (tingling and numbness of feet and hand)

Gastro-esophageal reflux disease

Hypercholesterolemia (high cholesterol)

Bronchitis (inflammation of the airways)

Contra Indications

Contraindications include ocular or periocular infections and hypersensitivity. [22] Patients who have an ocular infection, who recently underwent ocular surgery, or have increased intraocular pressures should avoid ranibizumab use.

Pregnancy Related Information

Lucentis Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Lucentis Injection. Please consult your doctor.

Breast Feeding Related Information

Lucentis Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Indications

(ranibizumab injection) is indicated for the treatment of patients with: Neovascular (wet) age-related macular degeneration (wAMD) Macular edema following retinal vein occlusion (RVO) Diabetic macular edema (DME)

Interactions

Drug-Drug Interactions: Inform the doctor if you are using, have recently used or might use any other medicines.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform the doctor if you have/had an eye infection, eye inflammation, or stroke.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

It may cause temporary visual disturbances. Don't drive or do anything that requires mental focus until you know how Lucentis Injection affects you.

Inform your doctor if you experience increased eye pain and redness, blurred or decreased vision, or increased sensitivity to light.

Wear sunglasses if your eyes feel sensitive to light

Use eye drops if they are prescribed to you by your doctor.

Ask your doctor if you should avoid any particular activities.

Try to rest your eyes as much as possible (for at least a few hours).

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. Who should not take Lucentis Injection?

Lucentis Injection should not be taken by individuals who are allergic to the medication or have an active eye infection.

Q. What is the duration of treatment for Lucentis Injection?

Lucentis Injection is recommended to be initially administered by intravitreal injection (into the eye) once a month (approximately 28 days) for up to 3 months.

Q. What precautions should I take after taking Lucentis Injection?

After taking Lucentis Injection:<br>a. You should not wash your face and hair or shower for 48 hours<br>b. Avoid rubbing your eyes<br>c. Avoid swimming for a week. Consult your doctor in case of any doubts<br>d. Do not wear contact lenses immediately after injection. You may wear spectacles instead<br>e. Give complete rest to your eyes and do not strain by looking at television, mobile phones, or computer screens for 1-2 days.