Lupiclox 250 mg / 250 mg (Injection)

Manufacturer: Lupin Ltd

Salt Composition : Ampicillin(250mg), Cloxacillin(250mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Lupiclox 250 mg/250 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.


Basic Information

Mechanism Of Action

Lupiclox 250 mg/250 mg Injection is a combination of two antibiotics, Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively.

Pharmacokinets

Ampicillin is well-absorbed from the GI tract (though food reduces its absorption), and reaches peak concentrations in one to two hours. The bioavailability is around 62% for parenteral routes. Unlike other penicillins, which usually bind 60–90% to plasma proteins, ampicillin binds to only 15–20%.Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lupiclox

Allergic reaction

Rash

Stomach pain

Nausea

Diarrhea

Contra Indications

If you are suffering from any of the following diseases, you should not take Ampicillin + Cloxacillin unless your doctor advises you to do so -

Kidney Disease

Asthma

Liver Disease

Pregnancy Related Information

Lupiclox 250 mg/250 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

Consuming alcohol with Lupiclox 250 mg/250 mg Injection does not cause any harmful side effects.


Breast Feeding Related Information

Lupiclox 250 mg/250 mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Ampicillin+Cloxacillin is used to treat patients with bacterial infections. It is a semi-synthetic derivative of the drug penicillin. It is used to treat urinary tract and respiratory tract infections, meningitis, gonorrhea and infections of the stomach or intestine.

Interactions

AMPICILLIN+CLOXACILLIN may interact with sulphonamides, bacteriostatic drugs, combined oral contraceptives, drugs used to decrease uric acid (allopurinol), and pain killers (aspirin).

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Lupiclox 250 mg/250 mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

You have been prescribed this combination medicine to treat bacterial infections.

Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Diarrhea may occur as a side effect. Taking probiotics along with Lupiclox 250 mg/250 mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.

Take it with food and plenty of fluids to avoid an upset stomach.

Stop taking Lupiclox 250 mg/250 mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. How long does Lupiclox 250 mg/250 mg Injection takes to work?

Usually, Lupiclox 250 mg/250 mg Injection starts working soon after using it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Q. Can I stop taking Lupiclox 250 mg/250 mg Injection when I feel better?

No, do not stop taking Lupiclox 250 mg/250 mg Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Q. What is Lupiclox 250 mg/250 mg Injection used for?

Lupiclox 250 mg/250 mg Injection is used to treat patients with bacterial infections. It is a semi-synthetic derivative of the drug penicillin. It is used to treat urinary tract and respiratory tract infections, meningitis, gonorrhea and infections of the stomach or intestine.

Q. Which medicines should be avoided while taking Lupiclox 250 mg/250 mg Injection?

Lupiclox 250 mg/250 mg Injection should be avoided with methotrexate which is used to treat rheumatoid arthritis, psoriasis and some forms of cancer. This is because combining the two medications can cause some serious side effects.