Lupicold Forte Tablet (10'S)


This medication may be taken with or without food and It is better to take it in a dose and duration as advised by the doctor. Before taking this medicine, tell your doctor if you have asthma, hypertension or any type of heart problem.

Dizziness may occur as its side effect, so do not drive or do anything that requires mental focus.


Basic Information

Mechanism Of Action

Lupicold Forte Tablet is a decongestant. It works by inducing release of norepinephrine hormone, which activates the andregenic receptor proteins in the body. The activation of these receptors causes the blood vessels to constrict in the sinus, nose and chest to alleviate congestion.

Pharmacokinets

Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lupicold Forte

Systemic hypertension (high blood pressure)

Insomnia (difficulty in sleeping)

Rash

Headache

Dizziness

Blurred vision

Nausea

Dry nose

Constipation

Dryness in mouth

Chills

Urticaria

Photosensitivity

Increased sweating

Dry throat

Palpitations

High blood pressure

Vomiting

Decreased appetite

Diarrhea

Restlessness

Anxiety

Tremors

Excitement

Epigastric pain

Contra Indications

If you are suffering from any of the following diseases, you should not take Dexchlorpheniramine + Phenylpropanolamine unless your doctor advises you to do so -

Heart Disease

Hyperthyroidism

Liver Disease

Kidney Disease

Glaucoma

Asthma

Gastrointestinal Bleeding

Diabetes

Heart Disease

Glaucoma

Pregnancy Related Information

Lupicold Forte Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Lupicold Forte Tablet may cause excessive drowsiness with alcohol.


Breast Feeding Related Information

Information regarding the use of Lupicold Forte Tablet during breastfeeding is not available. Please consult your doctor.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

This combination medication contains antihistamine and decongestant, prescribed for nasal congestion, runny nose, sneezing, itchy nose or throat and itchy or watery eyes due to the common cold or allergic rhinitis.

Interactions

Acebutolol

Alcohol

Anxiolytic sedatives

Atropine

Barbiturates

Bromocriptine

Debrisoquine

Doxepin

Ephedrine

Furazolidone

Typical Dosage

Do not chew, crush or break it. Lupicold Forte Tablet is to be taken with food.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Lupicold Forte Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Phenylpropanolamine

Do not continue phenylpropanolamine for more than 7 days if your condition does not improve or if you have high fever.

Tell your doctor if you have high blood pressure, heart problems, liver or kidney disease, diabetes, prostate enlargement or visual problems due to increased pressure in the eyes (glaucoma).

Seek immediate medical attention and discontinue medication if you experience difficulty in breathing, sudden swelling or skin reactions, fits, rapid heartbeat or hallucinations.

Use with caution if you are a woman or an elderly patient. Woman may be at a higher risk of haemorrhagic stroke (bleeding in the brain).

Avoid driving or operating machinery if you feel dizzy or drowsy after taking phenylpropanolamine.

Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Do not take if allergic to phenylpropanolamine or any of its ingredients.

Dexchlorpheniramine

Avoid driving or operating dangerous machinery as it may decrease alertness.

Avoid consuming alcohol when taking the Dexchlorpheniramine, as it may cause excessive sleepiness or drowsiness.

Dexchlorpheniramine should not be used in children less than 12 years of age.

Patients with other underlying medical conditions must consult their doctor before taking Dexchlorpheniramine.

Dexchlorpheniramine should not be taken by patients taking Monoamine oxidase inhibitors, such as isocarboxazid, phenelzine, tranylcypromine, etc.

Pregnant and breastfeeding mothers should not take this medicine unless prescribed by a doctor.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupicold Forte Tablet is to be taken with food.

FAQs

Phenylpropanolamine

Q. Is phenylpropanolamine the same as phenylephrine?

Phenylpropanolamine and phenylephrine are different drugs belonging to the same class of medications (nasal decongestants). Both are used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever)

Q. Does Phenylpropanolamine cause stroke?

Phenylpropanolamine has shown to increase the risk of hemorrhagic stroke (bleeding in the brain). Women are at a higher risk.

Q. Is Phenylpropanolamine a controlled substance?

Phenylpropanolamine is a controlled substance since it can be used for manufacturing of illegal drugs

Q. Is Phenylpropanolamine still on the market?

Phenylpropanolamine is banned in India due to increased risk of haemorrhagic stroke (bleeding in the brain) and is no longer marketed in India

Dexchlorpheniramine

Q. Does dexchlorpheniramine or dexchlorpheniramine maleate cause increase in blood pressure/ drowsy/non drowsy/sedating/get you high/keep you awake/sleepiness/make you tired/weight gain?

Dexchlorpheniramine causing these side effects is common or rare. Always consult your doctor if you experience any of these side effects

Q. Is dexchlorpheniramine like Benadryl?

No, dexchlorpheniramine is different from Benadryl

Q. Is dexchlorpheniramine prescription?

Yes, it is available with doctor's prescription only

Q. Can I take dexchlorpheniramine with Panadol/cetirizine/Zyrtec/Allegra/ warfarin/diphenhydramine/ibuprofen/Claritin/guaifenesin/Benadryl?

Yes, but taking other medicines may alter the effects of dexchlorpheniramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.