Manufacturer: Lupin Ltd
Salt Composition : Filgrastim(300mcg)
Lupifil 300mcg Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.
The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Lupifil 300mcg Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.
Filgrastim is a short-acting recombinant G-CSF that mimics the biological actions of endogenous G-CSF. It also facilitates the release of neutrophils from the bone marrow into the blood to reduce the incidence of infection and manage neutropenia. Filgrastim exhibits nonlinear pharmacokinetics.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lupifil
Bone pain
Weakness
Headache
Rash
Nausea
Increased lactate dehydrogenase level in blood
Vomiting
Increased uric acid level in blood
Oropharyngeal pain
Hair loss
Fatigue
Diarrhea
Constipation
Decreased appetite
Cough
Breathing problems
Injection site reactions (pain, swelling, redness)
If you are suffering from any of the following diseases, you should not take Filgrastim unless your doctor advises you to do so -
Drug Allergy
Heart Disease
Respiratory Distress Syndrome
Sickle Cell Disease
Blood Cancer
Sideroblastic Anemia
Lupifil 300mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Lupifil 300mcg Injection. Please consult your doctor.
Lupifil 300mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Filgrastim is indicated to decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a significant incidence of severe neutropenia with fever.
FILGRASTIM may have interaction with other hematopoietic agents (pegfilgrastim), medicines used to treat cancer (altretamine, bendamustine, carboplatin, busulfan, cladribine, alemtuzumab, bevacizumab, dinutuximab, gemtuzumab, procarbazine, dacarbazine. )
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Lupifil 300mcg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Lupifil 300mcg Injection reduces the risk of infection in people treated with chemotherapy.
It is usually given as a daily injection into the tissue just under the skin or into the vein.
You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
Store it in the refrigerator, protect it from light, and don't shake it.
For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
Use caution while driving or doing anything that requires concentration as Lupifil 300mcg Injection may cause dizziness.
Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
Stop taking Lupifil 300mcg Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Lupifil 300mcg Injection safe?
Lupifil 300mcg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. How does Lupifil 300mcg Injection work?
Lupifil 300mcg Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.
Q. What are the uses of Lupifil 300mcg Injection?
Lupifil 300mcg Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.
Q. Does Lupifil 300mcg Injection cause cancer?
No, Lupifil 300mcg Injection does not cause cancer.
Q. Why does Lupifil 300mcg Injection cause bone pain?
The exact cause in unknown, but bone pain is a common side-effect of Lupifil 300mcg Injection.
