Manufacturer: Lupin Ltd
Salt Composition : Buprenorphine(0.3mg)
Vial of 2ml Injection
(Inclusive of all taxes)
Lupigesic-Old 0.3mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should continue receiving the medicine until the doctor tells you it is alright to stop.
The most common side effects of this medicine include weakness, drug withdrawal syndrome, anxiety, nervousness, dizziness, headache, sleepiness, diarrhea, nausea, vomiting, and abdominal pain. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have any respiratory disorders, problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Lupigesic-Old 0.3mg Injection is a opioid partial agonist that provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.
Buprenorphine is metabolized by the liver, via CYP3A4 (also CYP2C8 seems to be involved) isozymes of the cytochrome P450 enzyme system, into norbuprenorphine (by N-dealkylation).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lupigesic-Old
Weakness
Anxiety
Nervousness
Dizziness
Drug withdrawal syndrome
Headache
Sleepiness
Diarrhea
Nausea
Vomiting
Abdominal pain
If you are suffering from any of the following diseases, you should not take Buprenorphine unless your doctor advises you to do so -
Liver Disease
Asthma
COPD (Chronic Obstructive Pulmonary Disease)
Jaundice
Heart Disease
Diabetes
Kidney Disease
Lupigesic-Old 0.3mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Lupigesic-Old 0.3mg Injection.
Lupigesic-Old 0.3mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Buprenorphine has three FDA indications: opioid detoxification, opioid maintenance, and pain management. Opioid detoxification describes the process in which a physically dependent individual is gradually tapered off all opioids.
impaired GI motility
infectious diarrhea
liver disease
prematurity
gastrointestinal obstruction
acute MI
drug dependence
intracranial pressure
respiratory depression
adrenal insufficiency
biliary spasm
hypothyroidism
renal dysfunction
seizure disorders
urinary retention
Kindly do not self administer.
Store below 30°C
If you miss a dose of Lupigesic-Old 0.3mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Lupigesic-Old 0.3mg Injection is given as an injection by healthcare professionals only.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Lupigesic-Old 0.3mg Injection can cause dizziness and sleepiness.
Avoid drinking alcohol or taking other medicines that can cause drowsiness.
Discontinue the medicine and inform your doctor if you experience difficulty breathing.
Do not stop taking Lupigesic-Old 0.3mg Injection without talking to your doctor first as it may cause a worsening of symptoms.
Your doctor may get regular blood tests to check for liver function while taking this medicine.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is Lupigesic-Old 0.3mg Injection used for?
Lupigesic-Old 0.3mg Injection is used to relieve severe pain when other pain medicines did not work well enough or cannot be tolerated. This medicine is not used for minor pain or pain that only sometimes occurs. It should not be used to treat pain that you only have once in a while or "as needed". It is also used to treat opioid use disorder.
Q. How is Lupigesic-Old 0.3mg Injection given?
This medicine should be injected into the skin and never into a vein. Injecting Lupigesic-Old 0.3mg Injection into a vein or muscle could result in damage to the skin or underlying tissues, as well as a blood clot that could be fatal.
Q. How fast Lupigesic-Old 0.3mg Injection start to work after IV (intravenous) administration?
The analgesic (pain-relieving) effect after IV administration usually occurs within 10-30 minutes and the peak effects occur within 60 minutes.
Q. How long the analgesic effect of Lupigesic-Old 0.3mg Injection lasts?
The analgesic effect of Lupigesic-Old 0.3mg Injection usually lasts for an average of six hours but the duration may vary between individuals.
Q. After administration of Lupigesic-Old 0.3mg Injection, I can feel a small lump under your skin. Is this normal?
Yes, you may see or feel a small lump under your skin where the medicine was injected. This could last for several weeks but the lump might eventually get smaller. Avoid rubbing or massaging the lump, or wearing tight clothing over the area. Consult your doctor if it worries you.
Q. When should I see my doctor?
The person caring for you should seek medical help immediately if you have slow breathing with long pauses, blue-colored lips, or if you are hard to wake up.
Q. Can I take alcohol with Lupigesic-Old 0.3mg Injection?
This medicine may cause sleepiness or dizziness and affect your ability to drive or operate machinery. Avoid alcohol and consult your doctor in case of any doubts.
Q. I feel dizzy when I get up from a sitting position or when I walk down the stairs. Is it due to Lupigesic-Old 0.3mg Injection?
This medicine may cause a severe lowering of blood pressure, or a sudden drop in blood pressure when going from sitting to standing, especially if you are taking medications for high blood pressure. Talk to your doctor who might change your dosage.
Q. Can Lupigesic-Old 0.3mg Injection cause addiction?
This medicine may be addictive and cause psychological dependence and withdrawal symptoms, particularly when used for long periods of time.
Q. Can I use Lupigesic-Old 0.3mg Injection during pregnancy?
If you use Lupigesic-Old 0.3mg Injection while you are pregnant, your baby could become dependent on the medicine. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.
Q. Can I use Lupigesic-Old 0.3mg Injection while breastfeeding?
Lupigesic-Old 0.3mg Injection can pass into breast milk and may cause drowsiness, and breathing problems in a breastfeeding baby. Ask your doctor in detail about all the risks.
