Manufacturer: Lupin Ltd
Salt Composition : Dicyclomine(20mg), Paracetamol(500mg)
Lupispas Plus 20 mg/500 mg Tablet is taken with or without food in a dose and duration as advised by the doctor. It is better to take it with food to avoid stomach upset. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, dryness in the mouth, blurred vision, weakness, and nervousness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. You should also tell your doctor if you are breastfeeding.
Lupispas Plus 20 mg/500 mg Tablet effectively relieves sudden muscle spasms or contractions in the stomach and intestine (gut), thereby relaxing the muscles and improving the movement of food. It also blocks chemical messengers in the brain that are responsible for pain sensation.
Dicyclomine is an antimuscarinic agent used to treat IBS. Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lupispas Plus
Nausea
Dryness in mouth
Blurred vision
Sleepiness
Weakness
Nervousness
Hypersensitivity to Lupispas Plus Tablet is a contraindication. In addition, Lupispas Plus Tablet should not be used if you have the following conditions:
Glaucoma
Hepatic impairment
Hypersensitivity
Infants less than 6 months of age
Myasthenia gravis
Nursing mothers
Obstructive disease of the gastrointestinal tract
Obstructive uropathy
Severe ulcerative colitis
Unstable cardiovascular status in acute hemorrhage
Lupispas Plus 20 mg/500 mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Lupispas Plus 20 mg/500 mg Tablet.
Lupispas Plus 20 mg/500 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Dicyclomine+Paracetamol is used in the treatment of abdominal pain. It relieves abdominal pain that is associated with biliary colic, intestinal colic, renal colic and dysmenorrhea.
If you use other drugs or over the counter products at the same time, the effects of Lupispas Plus Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Lupispas Plus Tablet may interact with the following drugs and products:
Alcohol
Amantadine
Antacids
Antihistamines
Benzodiazepines
Corticosteroids
Digoxin
Interfere with certain laboratory tests
Juxtapid mipomersen
Ketoconazole
Do not chew, crush or break it. Lupispas Plus 20 mg/500 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Lupispas Plus 20 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Lupispas Plus 20 mg/500 mg Tablet helps relieve stomach pain.
Take it with food to prevent an upset stomach.
If you get diarrhea while taking this medicine you should stop taking it and consult your doctor.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
Avoid consuming alcohol while taking this medicine as it can cause excessive drowsiness and increase your risk of stomach problems.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupispas Plus 20 mg/500 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Lupispas Plus 20 mg/500 mg Tablet?
Lupispas Plus 20 mg/500 mg Tablet is a combination of two medicines: Dicyclomine and Paracetamol. This medication helps in relieving stomach pain. It works by relaxing the muscles of the stomach and intestine by decreasing the levels of chemical substances in the body that cause pain.
Q. Is it safe to use Lupispas Plus 20 mg/500 mg Tablet?
Lupispas Plus 20 mg/500 mg Tablet is safe for most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, dryness of mouth, blurred vision, sleepiness, weakness and nervousness. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.
Q. Can I stop taking Lupispas Plus 20 mg/500 mg Tablet when my pain is relieved?
Lupispas Plus 20 mg/500 mg Tablet is usually used for short-term and can be discontinued if there is no pain. However, it should be continued if you are advised by your doctor to do so.
Q. Can the use of Lupispas Plus 20 mg/500 mg Tablet cause diarrhea?
Yes, the use of Lupispas Plus 20 mg/500 mg Tablet can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids by taking small frequent sips. Also, avoid taking fatty or fried foods along with this medication. Talk to your doctor if diarrhea persists and you notice signs of dehydration, like less urination with dark colored and strong-smelling urine. Do not take any other medicine without speaking to your doctor.
Q. Can the use of Lupispas Plus 20 mg/500 mg Tablet cause dry mouth?
Yes, the use of Lupispas Plus 20 mg/500 mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.
Q. Are there any specific contraindications associated with the use of Lupispas Plus 20 mg/500 mg Tablet?
The use of Lupispas Plus 20 mg/500 mg Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. It should be used carefully in patients with alcohol dependency or with underlying kidney or liver damage.
Q. Can the use of Lupispas Plus 20 mg/500 mg Tablet cause damage to liver?
Lupispas Plus 20 mg/500 mg Tablet is usually safe to use in the dose as recommended by the doctor. However, an overdose of Lupispas Plus 20 mg/500 mg Tablet can cause damage to the liver. Avoid drinking alcohol while taking this medicine, as it may further increase the risk of liver damage. Use of this medicine is not recommended in patients with the severe liver disease.
Q. Can I take a higher dose of this medicine than recommended?
No, taking higher than the recommended dose of Lupispas Plus 20 mg/500 mg Tablet can lead to increased chances of side effects. If you are experiencing increased severity of pain or if the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. What are the instructions for storage and disposal of Lupispas Plus 20 mg/500 mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.