Manufacturer: Lupin Ltd
Salt Composition : Rituximab(100mg)
Lupiximab 100mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.
Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Lupiximab 100mg Injection is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.
Rituximab follows a linear pharmacokinetic model. In patients with non-Hodgkin's lymphoma (NHL) administered 4 doses of 375 mg/m2 of rituximab (IV) weekly, detectable levels were observed 3-6 months after treatment completion.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lupiximab
Headache
Weakness
Infection
Chills
Decreased white blood cell count (neutrophils)
Fever
Infusion site reaction
Lymphopenia
Abdominal pain
Back pain
If you are suffering from any of the following diseases, you should not take Rituximab unless your doctor advises you to do so -
Hyperkalemia
Kidney Disease
Infections
Anemia
Heart Disease
Neutropenia
Lupiximab 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Lupiximab 100mg Injection. Please consult your doctor.
Lupiximab 100mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
RITUXAN (rituximab) is indicated for the treatment of adult patients with: Relapsed or refractory, low-grade or follicular, CD20-positive, B-cell NHL as a single agent.
If you use other drugs or over the counter products at the same time, the effects of Lupiximab Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Lupiximab Injection may interact with the following drugs and products:
Adalimumab
Certolizumab
Clozapine
Deferiprone
Etanercept
Fingolimod
Golimumab
Infliximab
Leflunomide
Natalizumab
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Lupiximab 100mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
It is given as a drip (intravenous infusion) by your doctor or nurse.
You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Inform your doctor if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
