Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Rituximab(500mg)
Mabtas 500 Infusion is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.
Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Mabtas 500 Infusion is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.
In conclusion, the magnitude of the effect of absorption modifiers is dependent on the site of injection and the dose level of rituximab. Pharmacokinetic profiles further support the hypothesis that neonatal Fc receptor-mediated transport is a major determinant of s.c. absorption of mAbs.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mabtas
Headache
Weakness
Infection
Chills
Decreased white blood cell count (neutrophils)
Fever
Infusion site reaction
Lymphopenia
Abdominal pain
Back pain
Severe, active infection.
Hypersensitivity to any of the components of the formulation.
Severe heart failure.
Uncontrolled cardiac disease.
Pregnancy.
Mabtas 500 Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Mabtas 500 Infusion. Please consult your doctor.
Mabtas 500 Infusion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CD20 positive B-cell Non-Hodgkin's Lymphoma (NHL)
Chronic Lymphocytic Leukemia (CLL)
Rheumatoid Arthritis.
Microscopic Polyangiitis (MP) and Granulomatosis with Polyangiitis (GPA)
Pemphigus Vulgaris (PV)
Drug-Drug Interactions: RITUXIMAB may interact with vaccines, antineoplastic drugs (cisplatin), and other medicines.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease, gastrointestinal disorders, and pulmonary disorders before receiving RITUXIMAB.
Drug-Drug Interactions Checker List:
CISPLATIN
TYPHOID VACCINE
CHOLERA VACCINE
Kindly do not self-administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Mabtas 500 Infusion, please consult your doctor.\n
Consult a doctor before taking any medicines.
It is given as a drip (intravenous infusion) by your doctor or nurse.
You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Inform your doctor if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
