Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Rituximab(100mg)
Mabtas T 100mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.
Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Mabtas T 100mg Injection is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.
Rituximab follows a linear pharmacokinetic model. In patients with non-Hodgkin's lymphoma (NHL) administered 4 doses of 375 mg/m2 of rituximab (IV) weekly, detectable levels were observed 3-6 months after treatment completion.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mabtas N
Headache
Weakness
Infection
Chills
Decreased white blood cell count (neutrophils)
Fever
Infusion site reaction
Lymphopenia
Abdominal pain
Back pain
Severe, active infection.
Hypersensitivity to any of the components of the formulation.
Severe heart failure.
Uncontrolled cardiac disease.
Pregnancy.
Mabtas T 100mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Mabtas T 100mg Injection. Please consult your doctor.
Mabtas T 100mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Approved for use as a single agent in relapsed/refractory, low-grade, or follicular B cell NHL
Single-agent maintenance therapy for patients with previously untreated follicular B cell NHL who are achieving a complete or some degree of response to combination chemotherapy with rituximab
As a single agent in low-grade non-progressive/stable B cell NHL after CVP chemotherapy.
In combination with anthracycline-based chemotherapy in previously untreated diffuse large B cell NHL
amphotericin B deoxycholate.
belatacept.
cholera vaccine.
cisplatin.
denosumab.
fingolimod.
ioversol.
sipuleucel-T.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Mabtas T 100mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
It is given as a drip (intravenous infusion) by your doctor or nurse.
You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Inform your doctor if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
