Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Magnesium Valproate(200mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Macorate 200 Tablet can be used alone or in combination with other medicines. It may be taken with or without food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine, unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.
The most common side effects of this medicine include skin rashes, headache, feeling or being sick, difficulty sleeping, dizziness, and feeling sleepy or drowsy. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects. Long-term treatment can cause weakness in your bones (osteoporosis), increasing your risk of breaking a bone.
Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression, or suicidal thoughts. Also let your healthcare team know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.
Macorate 200 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
The pharmacokinetics of valproate have been studied in 27 patients with focal or generalized epilepsy taking a single daily dose of prolonged-release valproate given in the evening [305]. In about 60% of the patients the serum concentration measured at 0900 h corresponded to the peak value.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Macorate
Headache
Dizziness
Blurred vision
Loss of appetite
Nausea
Vomiting
Sleepiness
Hair loss
Weight gain
Double vision
Diarrhea
Impaired coordination
Tremors
Weakness
Stomach pain
Increased appetite
VPA is contraindicated in patients with significant hepatic impairment, hypersensitivity to components of the drug or its class, urea cycle disorders, mitochondrial disorders, suspected disorders in patients younger than 2, and during pregnancy, especially for migraine prophylaxis with VPA.
Macorate 200 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Macorate 200 Tablet. Please consult your doctor.
Macorate 200 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
MAGNESIUM VALPROATE belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, MAGNESIUM VALPROATE also treats bipolar disorder and prevents migraine headaches. MAGNESIUM VALPROATE decreases the brain's excessive and abnormal nerve activity, thereby controlling seizures.
Drug-Drug Interactions: MAGNESIUM VALPROATE may have interacted with anti-epileptic medicines (e.g. carbamazepine, lamotrigine), anti-depressant medicines (e.g. amitriptyline, sertraline), anti-psychotic medicines (e.g. quetiapine, olanzapine, risperidone), medications used to control seizures or fits due to epilepsy (e.g. clonazepam, diazepam, lorazepam).
Drug-Food Interactions: Avoid alcohol consumption while taking MAGNESIUM VALPROATE as it might cause increased dizziness and sleepiness.
Drug-Disease Interactions: MAGNESIUM VALPROATE may interact with disease conditions such as depression, liver disease, urea cycle disorders, suicidal tendencies, HIV, thyroid disease, and thrombocytopenia (low platelets).
Drug-Drug Interactions Checker List:
CARBAMAZEPINE
LAMOTRIGINE
AMITRIPTYLINE
SERTRALINE
QUETIAPINE
OLANZAPINE
RISPERIDONE
CLONAZEPAM
DIAZEPAM
LORAZEPAM
Do not chew, crush or break it. Macorate 200 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Macorate 200 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Consult a doctor before taking any medicines.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
Practice yoga every day.
Get enough sleep at nighttime.
Limit the use of screen time such as mobile/laptop.
Take your medication on time.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macorate 200 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. For how long should I take Macorate 200 Tablet to cure my epilepsy completely?
Macorate 200 Tablet does not cure your condition, it only prevents the seizures from occurring. Therefore, you will have to keep on taking it, maybe for years. Consult your doctor if face any problems while taking this medicine.
Q. What happens if I stop taking Macorate 200 Tablet?
You should not stop taking Macorate 200 Tablet suddenly. It should be discontinued gradually. Stopping it suddenly may increase the chances of recurrence of seizures. Always consult your doctor if you feel the need to stop taking this medicine.
Q. I have gained weight after I started using Macorate 200 Tablet. Is it because of this medicine? What should I do?
Yes, weight gain can occur with the use of Macorate 200 Tablet. To control your weight, you should have a healthy balanced diet and exercise regularly. Talk to your doctor if you have any other concerns.
Q. Can I take birth control pills while taking Macorate 200 Tablet?
Yes, Macorate 200 Tablet does not have any effect on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Macorate 200 Tablet and seizures may occur. It is important that you inform your doctor that you are using birth control pills. Your doctor will keep a track on your response to the treatment and monitor the Macorate 200 Tablet levels in your blood levels.
