Macugen 0.3mg Infusion (90ml)

Manufacturer: Pfizer Ltd

Salt Composition : Pegaptanib(0.3mg)


Macugen 0.3mg Infusion is administered directly into the eyeball by an eye specialist. You should not self administer this medicine at home. The common side effects include eye pain, redness, blurred or decreased vision and eye discharge.


However, if you experience these side effects for a longer duration or any other symptoms which you think may be due to this medicine, please inform your doctor. It is not advised to drive after administration of this injection as you may feel sleepy or dizzy and your alertness may be reduced.


Basic Information

Mechanism Of Action

Macugen 0.3mg Infusion is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the growth and leakage of abnormal blood vessels in the eye(s) that may cause vision loss.

Pharmacokinets

Pegaptanib exhibits “flip-flop” kinetics, a phenomenon wherein the drug remains in the eye for a significant amount of time, is slowly cleared into the systemic circulation, and then is relatively rapidly cleared from the circulation.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macugen

Foreign body sensation in eyes

Increased intraocular pressure

Eye pain

Punctate keratitis

Eye floaters

Visual impairment

Cataract

Blurred vision

Eye inflammation

Stinging in the eyes

High blood pressure

Corneal edema

Eye itching

Conjunctival hemorrhage

Burning sensation in eye

Eye discharge

Contra Indications

Most adverse events elated to the drug are ocular however non-ocular adverse events related to the drug or the injection procedure also occurred, among which headaches and rhinorrhoea appeared in more than 1% of patients. Pegaptanib is contraindicated when the patient has an ocular or periocular infection.

Pregnancy Related Information

Macugen 0.3mg Infusion is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Macugen 0.3mg Infusion. Please consult your doctor.

Breast Feeding Related Information

Macugen 0.3mg Infusion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Indications

Macugen (pegaptanib sodium) Injection decreases the level of a protein that affects the cells of the eye and is used to treat age-related macular degeneration.


Interactions


No interactions found.

Typical Dosage

Kindly do not self-administer.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Macugen 0.3mg Infusion, please consult your doctor.\n

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Macugen 0.3mg Infusion is used for the treatment of an eye condition called wet age-related macular degeneration.

It is administered directly into the eyeball by an eye specialist.

It may cause temporary visual disturbances. Don't drive or do anything that requires mental focus until you know how Macugen 0.3mg Infusion affects you.

Inform your doctor if you experience increased eye pain and redness, blurred or decreased vision, or increased sensitivity to light.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self-administer.