Manufacturer: Mankind Pharma Ltd
Salt Composition : Chlorzoxazone(250mg), Diclofenac(50mg), Paracetamol(500mg)
Mahadiclo Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.
Using this medicine can cause some common side effects such as nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, and dryness in the mouth. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.
The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.
Mahadiclo Tablet is a combination of a muscle relaxant (Chlorzoxazone) and two pain relieving medicines (Diclofenac and Paracetamol). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving movement of muscles. The pain relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling).
Diclofenac is over 99.7% bound to serum proteins, primarily albumin. It is undergoes limited binding to lipoproteins as well with 1.1% bound to HDL, 0.3% to LDL, and 0.15% to VLDL. Diclofenac undergoes oxidative metabolism to hydroxy metabolites as well as conjugation to glucuronic acid, sulfate, and taurine. Paracetamol is also well absorbed from the rectum. It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Chlorzoxazone is rapidly metabolized in the liver and is excreted in the urine, primarily in a conjugated form as the glucuronide. Chlorzoxazone is rapidly metabolized and is excreted in the urine, primarily in a conjugated form as the glucuronide.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mahadiclo
Nausea
Vomiting
Heartburn
Stomach pain
Diarrhea
Loss of appetite
Dryness in mouth
If you are experiencing bleeding from stomach and intestine or have an active peptic ulcer.
If you are allergic to other painkillers such as aspirin and have experienced severe asthma, rashes or any other allergy.
If you are suffering from any heart disease like heart failure and high blood pressure.
If you have problems with kidney and liver function.
If you are pregnant or elderly (65 years of age or older).
This medicine should not be used for relieving pain before, during and after bypass surgery of heart.
Information regarding the use of Mahadiclo Tablet during pregnancy is not available. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Mahadiclo Tablet. Please consult your doctor.
Information regarding the use of Mahadiclo Tablet during breastfeeding is not available. Please consult your doctor.
CHLORZOXAZONE+DICLOFENAC+PARACETAMOL is used in the reduction of musculoskeletal pain due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Pain can be temporary (acute) or long term(chronic) in nature.
Drug-Drug Interaction: CHLORZOXAZONE+DICLOFENAC+PARACETAMOL is shown to interact with various drugs. Some of them include pain killers (naproxen, aspirin, ibuprofen, tramadol, hydrocodone, oxycodone), blood pressure-related drugs (lisinopril, hydrochlorothiazide), blood thinner (rivaroxaban, warfarin), anti-depressant (duloxetine), acidity lowering drug (cimetidine), and steroids (prednisone). These drugs may affect the working of CHLORZOXAZONE+DICLOFENAC+PARACETAMOL and may alter its efficacy.
Drug-Food Interaction: Excessive intake of caffeine-containing food or drinks like coffee, tea, chocolate and some fizzy drinks should be avoided while taking CHLORZOXAZONE+DICLOFENAC+PARACETAMOL. Taking together may lead to drowsiness and dizziness and sleepiness.
Drug-Disease Interaction: CHLORZOXAZONE+DICLOFENAC+PARACETAMOL should not recommend for people having bleeding disorders, like haemophilia, von Willebrand disease or low blood platelets. Besides this, it should not be given in the condition of liver disease like jaundice, alcoholism and PKU phenylketonuria (birth defect with an excess of protein in the body).
Do not chew, crush or break it. Mahadiclo Tablet is to be taken with food.
Treatment of Pain due to muscle spasm
Store below 30°C
If you miss a dose of Mahadiclo Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Mahadiclo Tablet to relieve pain due to muscle spasm.
This medicine is most effective when taken along with proper rest and physical therapy.
Avoid consuming alcohol when taking Mahadiclo Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Mahadiclo Tablet.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Q. What is Mahadiclo Tablet?
Mahadiclo Tablet is a combination of three medicines: Diclofenac, Paracetamol, and Chlorzoxazone. This medication helps in relieving muscle pain. Chlorzoxazone is a muscle relaxant which works by acting on the central nervous system. Diclofenac and Paracetamol work by lowering the chemical substance (prostaglandins) in the body that causes pain and inflammation.
Q. Is it safe to use Mahadiclo Tablet?
Mahadiclo Tablet is safe for most of the patients. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, stomach pain, diarrhea, loss of appetite, dryness in the mouth, weakness, sleepiness and other uncommon or rare side effects. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.
Q. Can I stop taking Mahadiclo Tablet when my pain is relieved?
Mahadiclo Tablet should be continued if advised for a specific time duration by your doctor. However, it can be discontinued if you are using it for short-term pain relief.
Q. Can the use of Mahadiclo Tablet cause nausea and vomiting?
Yes, the use of Mahadiclo Tablet can cause nausea and vomiting. In case, you experience nausea while taking this medicine, take it with milk, food or with antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
