Manufacturer: Biocon
Salt Composition : Sulbactam(2gm)
Matabac 2gm Injection is a type of antibiotic belonging to a class known as beta-lactamase inhibitors. This medicine helps to make the bacteria more sensitive to antibiotic activity. It is given by drip (intravenous infusion) or by direct injection into a vein, under the supervision of a healthcare professional. It should be used regularly at evenly spaced intervals, as per the schedule prescribed by your doctor.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.
Before taking this medicine, inform your doctor if you have a history of an allergic reaction to this medicine or penicillin group of medicines. Diarrhea and local pain, swelling, or redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.
Matabac 2gm Injection is a beta-lactamase inhibitor. It works by blocking an enzyme called beta lactamase produced by bacteria to inactivate antibiotics. Matabac 2gm Injection is frequently combined with beta-lactam antibiotics, such as ampicillin, cefoperazone, meropenem. As a single medicine, it treats infection caused by a type of bacterium called Acinetobacter baumanii. This activity is mediated by its interaction with certain proteins.
Sulbactam has pharmacokinetics in humans similar to those of ampicillin. The average peak serum level after intravenous infusion of 1 g is 60 µg/mL. The serum half-life is 1 hour.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Matabac
Injection site pain
Diarrhea
Hypersensitivity.
Clostridioides difficile Infection.
Concomitant Infectious Mononucleosis Infection.
Hepatic Dysfunction.
Matabac 2gm Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Matabac 2gm Injection does not cause any harmful side effects.
Matabac 2gm Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Bone and joint infection.
Pelvic inflammatory disease.
Peritonitis.
Respiratory tract infections.
Septicaemia.
Skin infections.
Urinary tract infection.
Some products that may interact with this drug include: aminoglycosides (such as gentamicin), "blood thinners" (such as warfarin), methotrexate, tetracyclines. This medication may interfere with certain lab tests (such as certain urine glucose tests), possibly causing false test results.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Matabac 2gm Injection, consult your doctor.
Consult a doctor before taking any medicines.
Matabac 2gm Injection is used in treatment of severe bacterial infections, in combination with certain antibiotics.
It is also used alone in the treatment of serious infections caused by pathogen Acinetobacter baumannii including those resistant to other antibiotics.
It is preferentially given as an injection directly into a vein over a period of 15-60 minutes.
When used alone, it is associated with few adverse effects, mainly pain at the injection site and diarrhea.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Why is Matabac 2gm Injection added to other antibiotics?
Matabac 2gm Injection added to other antibiotics like ampicillin, cefoperazone, etc., because Matabac 2gm Injection contains Sulbactam, a beta-lactamase inhibitor, which reduces resistance and enhances the activity of other antibiotics like ampicillin, cefoperazone, etc., against the bacteria.
Q. Who should not take Matabac 2gm Injection?
Matabac 2gm Injection should not be taken by an individual if he/she had an allergic reaction to ampicillin, sulbactam, or any penicillin antibiotic (such as penicillins or cephalosporins), or if he/she has a history of liver problems caused by ampicillin/sulbactam.
Q. What should I discuss with my doctor before receiving Matabac 2gm Injection?
Before taking Matabac 2gm Injection, you should tell your doctor if you have ever had an allergic reaction to Matabac 2gm Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Matabac 2gm Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Matabac 2gm Injection.
Q. Can I use a discolored solution of Matabac 2gm Injection?
No. You should not use Matabac 2gm Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.
