Manufacturer: Abbott
Salt Composition : Carbamazepine(100mg)
Mazetol 100 Tablet must be taken with or without food, but take it at the same time every day. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. Many other medicines can interfere with this medicine so tell your doctor about all the medicines you are taking to make sure it is safe.
You can take this medicine with or without food but take it regularly at the same time each day to get the maximum benefit. It is important to take this medicine for as long as you are advised, even if you feel well. Missing even a single dose may trigger a seizure and, if you stop taking it abruptly, your condition may get worse.
The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, unsteadiness (balance disorder), constipation, dry mouth, and itching. Some people may develop blurring of vision and slurred speech. Most of the side effects are not serious. However, let your doctor know straight away if you notice a skin rash or if your mood becomes depressed or if you develop any thoughts about harming yourself.
Before taking Mazetol 100 Tablet, tell your doctor if you have any heart problems, kidney or liver disease, difficulty in urinating, or any mental illness like depression. These conditions may affect your treatment. You may be advised some blood tests (eg. CBC) before starting treatment and then periodically thereafter, to monitor your progress.
Carbamazepine has been used as AEDs since 1965, and is most effective against partial seizures. Two basic mechanisms of action have been proposed: 1) enhancement of sodium channel inactivation by reducing high-frequency repetitive firing of action potentials, 2) and action on synaptic transmission.
After single doses of carbamazepine, elimination follows dose-dependent first order kinetics. Carbamazepine is metabolised by oxidation before excretion in the urine. In experimental animals, the metabolite carbamazepine-10,11-epoxide has anticonvulsant activity comparable with that of the parent drug.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mazetol
Dizziness
Nausea
Vomiting
Constipation
Sleepiness
Abnormality of voluntary movements
Carbamazepine is contraindicated in patients with bone marrow depression and hypersensitivity to this drug or tricyclic compounds such as amitriptyline. [20] Before administration, monoamine oxidase inhibitors should be discontinued for a minimum of 14 days.
Mazetol 100 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Mazetol 100 Tablet may cause excessive drowsiness with alcohol.
Mazetol 100 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Carbamazepine is used to manage and treat epilepsy, trigeminal neuralgia, and acute manic and mixed episodes in bipolar I disorder. Indications for epilepsy are specifically for partial seizures with complex symptomatology (psychomotor, temporal lobe), generalized tonic seizures (grand mal), and mixed seizure patterns.
Studies and case reports demonstrate that CBZ may accelerate the metabolism of phenytoin, phenobarbital (PB), primidone, valproic acid, and warfarin. Likewise, phenytoin, PB, and primidone may increase the hepatic metabolism of CBZ.
Do not chew, crush or break it. Mazetol 100 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Mazetol 100 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
Practice yoga every day.
Get enough sleep at nighttime.
Limit the use of screen time such as mobile/laptop.
Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Your doctor may get regular tests done to monitor the level of blood cells in your blood while taking this medication.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Inform your doctor if you notice a rash or other skin changes such as reddish spot or circular patches while taking this medicine.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mazetol 100 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How quickly does Mazetol 100 Tablet start working?
Your symptoms may take 1-2 weeks to improve. However, in some cases, it may take even longer. Consult your doctor if your condition doesn't improve or if you have any doubts regarding your condition.
Q. Is Mazetol 100 Tablet an analgesic? What is it used for?
No, Mazetol 100 Tablet is not an analgesic and should not be used for regular aches or pains. It is an anti-epileptic medicine which is used to treat fits (seizures). It is also used in the treatment of trigeminal neuralgia (intense facial nerve pain). In addition to that, Mazetol 100 Tablet is used to control mood disorders when other medicines fail to work.
Q. What should I tell my doctor before taking Mazetol 100 Tablet?
Inform your doctor if you are taking any other medicines including medicines for epilepsy or seizures, medicines used to thin your blood (e.g., warfarin), medicines to control bacterial infection (e.g., chloramphenicol, metronidazole and doxycycline) and medicines to control viral infection (e.g., nelfinavir). Also, let your doctor know if you take asthma medicines (e.g., theophylline and montelukast), birth control pills, etc. It is important to tell your doctor if you are planning to become pregnant or are breastfeeding. Further, you should tell the doctor if you have ever had liver problems, kidney problems, lung problems or porphyria (a rare blood pigment disorder).
Q. What are the long-term effects of Mazetol 100 Tablet?
The long-term side effects of Mazetol 100 Tablet vary from person to person. While some people can take Mazetol 100 Tablet safely for several years, some may develop side effects on using it for long term. These side effects include osteoporosis and osteopenia in which the bones become weak and can get easily fractured. Therefore, if you have been prescribed Mazetol 100 Tablet for a long term, get your bone density checked at regular intervals, maintain a healthy diet and exercise daily.
