Medistat 0.5mg Tablet (1'S)

Manufacturer: Alteus Biogenics Pvt Ltd

Salt Composition : Midazolam(0.5mg)


Medistat 0.5mg Tablet may be taken with or without food. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the exact dose and duration advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may cause nausea and anxiety. If you have been taking this medicine for a long time then regular monitoring of blood and liver functions may be required.


Some common side effects of this medicine include memory impairment, tiredness, depression, and confusion. It may cause dizziness and sleepiness so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.


Basic Information

Mechanism Of Action

Medistat 0.5mg Tablet is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Pharmacokinets

The pharmacokinetic variables of midazolam reveal that it is cleared significantly more rapidly than diazepam and lorazepam. The rapid redistribution of midazolam and high rate of liver clearance account for its relatively short hypnotic and hemodynamic effects.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Medistat

Memory impairment

Tiredness

Depression

Confusion

Dizziness

Sleepiness

Contra Indications

midazolam is contraindicated in patients with a known hypersensitivity to the drug. Benzodiazepines are contraindicated in patients with acute narrow-angle glaucoma. Benzodiazepines may be used in patients with open-angle glaucoma only if they are receiving appropriate therapy.

Pregnancy Related Information

Medistat 0.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product And Alcohol Interaction

Medistat 0.5mg Tablet may cause excessive drowsiness with alcohol.

Breast Feeding Related Information

Medistat 0.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Medistat 0.5mg Tablet should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Medistat 0.5mg Tablet should be gradual.

Indications

Intravenous midazolam is used for the induction of anesthesia and also in the management of acute seizures. Because of its water-soluble nature, midazolam has a rapid onset of action and can be used to manage status epilepticus when intravenous administration of other medications is not feasible.

Interactions

Drug-Drug Interaction: Inform your doctor if you are taking high blood pressure-lowering medicines (diltiazem, nifedipine, verapamil), antifungals (fluconazole, ketoconazole, voriconazole, itraconazole, posaconazole), antibiotics (clarithromycin, erythromycin, roxithromycin, rifampicin), high cholesterol-lowering medicines (atorvastatin), medicines for HIV/AIDS (saquinavir), anticonvulsants (phenytoin, carbamazepine), opioid pain killers (fentanyl), anti-allergic medicines, antianxiety drug (diazepam), antidepressants, and other medicines.

Drug-Food Interaction: MIDAZOLAM may interact with grapefruit. Therefore, avoid intake of grapefruit or grapefruit juice with MIDAZOLAM as it may increase the adverse effects of MIDAZOLAM. Also, avoid alcohol consumption with MIDAZOLAM as it may increase the sedative effect. Inform your doctor if you are taking St. John's wort (a herbal medicine).

Drug-Disease Interaction: If you have a lung or breathing disorder, myasthenia gravis (muscle weakness), history of drug abuse or personality disorder, or kidney, liver or heart problems, inform your doctor before taking MIDAZOLAM.

Drug-Drug Interactions Checker List:

DILTIAZEM

NIFEDIPINE

VERAPAMIL

FLUCONAZOLE

KETOCONAZOLE

VORICONAZOLE

ITRACONAZOLE

POSACONAZOLE

CLARITHROMYCIN

ERYTHROMYCIN

ROXITHROMYCIN

RIFAMPICIN

ATORVASTATIN

SAQUINAVIR

PHENYTOIN

CARBAMAZEPINE

FENTANYL

DIAZEPAM

Typical Dosage

Do not chew, crush or break it. Medistat 0.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Medistat 0.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor

It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.

Avoid consuming alcohol as it may increase dizziness and drowsiness.

Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Medistat 0.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

FAQs

Q. Is Medistat 0.5mg Tablet safe?

Medistat 0.5mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. Is Medistat 0.5mg Tablet a controlled substance?

Yes, Medistat 0.5mg Tablet is a controlled substance

Q. Is Medistat 0.5mg Tablet a sedative?

Yes, Medistat 0.5mg Tablet a sedative medication used before and during diagnostic or surgical procedures either in combination with or without local anesthesia

Q. Is Medistat 0.5mg Tablet a benzodiazepine?

Yes, Medistat 0.5mg Tablet belongs to benzodiazepine class of sedative medication