Manufacturer: View Laboratories
Salt Composition : Tramadol (NA)
Tube of 25gm Gel
(Inclusive of all taxes)
Medol Gel is only meant for external use and should be used strictly as advised by your doctor. A thin layer of the medicine should be rubbed into the affected areas with clean and dry hands. Avoid getting in contact with your eyes, nose, or mouth and avoid applying it on wounded or damaged skin. In case of accidental contact with these areas, you should rinse it with cold water.It is usually safe with little or no side effects. However, it may cause application site reactions such as redness, tingling, prickling, numbness, rash, and itching. These are usually temporary and resolve with time. If they do not get better with time or worsen, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Medol Gel helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Tramadol is extensively metabolized in the liver by O- and N-desmethylation and by conjugation reactions to form glucuronides and sulfate metabolites. The O-desmethylation of tramadol to its main active metabolite, O-desmethyltramadol (M1), is catalyzed by cytochrome P450 (CYP) 2D6 [19,20,32] (Fig.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Medol
Application site reactions (burning, irritation, itching and redness)
low blood sugar
decreased function of the adrenal gland
low amount of sodium in the blood
symptoms from alcohol withdrawal
suicidal behavior
suicidal thoughts
alcoholism
alcohol intoxication
drug abuse
depression
serotonin syndrome, a type of disorder with high serotonin levels
a low seizure threshold
asthma
decreased lung function
blockage of the stomach or intestine
hardening of the liver
seizures
opioid overdose
a patient who is producing milk and breastfeeding
benzodiazepine overdose
high pressure within the skull
nervous system infection of brain and spinal cord
inherited dysfunction of autonomic nerve function
chronic obstructive pulmonary disease
CYP2D6 ultrarapid metabolizer
CYP2D6 poor metabolizer
sleep apnea due to airway obstruction
surgical removal of the adenoids in pediatric patient
surgical removal of the tonsils in pediatric patient
chronic kidney disease stage 4 (severe)
chronic kidney disease stage 5 (failure)
chronic kidney disease stage 5 (failure) without dialysis GFR<15 mL/min
Medol Gel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Medol Gel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Use with caution
Below 9years: Contraindicated
It has specific indications for moderate to severe pain. It is considered a class IV drug by the FDA and has been since July 7th, 2014. Due to possible abuse and addiction potential, limitations to its use should be for pain that is refractive to other pain medication, such as non-opioid pain medication.
TRAMADOL may have interaction with pain killers (pentazocine, buprenorphine, nalbuphine), blood thinners (warfarin), anti-anxiety drugs (alprazolam), fits related medicines (carbamazepine), medicines used to prevent nausea (ondansetron), antifungal drugs (ketoconazole), antibiotic (ciprofloxacin, erythromycin), anticancer drugs (ceritinib, lapatinib), immunosuppressants (fingolimod), antidepressants (fluoxetine, doxepin), antipsychotics (droperidol), and HIV/AIDS drugs (saquinavir).
Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Store below 30°C
If you miss a dose of Medol Gel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.
Q. Is there anything I need to be careful about while on therapy with Medol Gel?
Medol Gel may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.
