Manufacturer: Themis Medicare Ltd
Salt Composition : Paracetamol(250mg)
Packet of 5 Suppository
(Inclusive of all taxes)
Metacin 250mg Suppository is for rectal use only and should never be taken by mouth. Encourage your child to empty the bowel before inserting the medicine as that will enhance the absorption of the medicine. Also, ask your child to slow down and avoid moving around a lot at least for an hour after placing the medicine. The dose will depend upon your child’s age, body weight, and severity of the infection, so stick to the dose, duration, and way prescribed by your child’s doctor. If your child passes stool within 30 minutes of inserting Metacin 250mg Suppository, you will have to insert it again.
Do not give your child Metacin 250mg Suppository along with other medicines (many cold and flu medicines and other painkillers) that contain paracetamol, as this may result in overdosing and cause dangerous side effects such as hepatotoxicity (liver damage). Always check the ingredients of any other medicine before giving them to your child in combination with this medicine. Also, do not stop giving the medicine abruptly even if your child starts to feel better. Doing so may bring back the symptoms or worsen the condition.
Generally, this medicine is well-tolerated by the children. However, temporary side effects such as anal irritation, nausea, vomiting, and constipation may occur in some children. Consult your doctor in case these episodes become bothersome for your child.
This medicine is often considered safe and effective but may not be suitable for everybody. Inform your doctor if your child is undergoing treatment for any blood-related disorder, is allergic to any medicinal compound, or has any birth defects, liver impairment, or kidney dysfunction. This will help your child’s doctor evaluate the dose and suitability of this medicine in a better way.
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors.
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Metacin 250mg Suppository does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Metacin
Anal irritation
Constipation
Stomach pain
Nausea
Vomiting
caloric undernutrition.
acute liver failure.
liver problems.
a condition where the body is unable to maintain adequate blood flow called shock.
acetaminophen overdose.
acute inflammation of the liver due to hepatitis C virus.
The dose and duration will depend upon your child’s age, body weight, and severity of the infection, so stick to the dose, time, and way prescribed by your child’s doctor.
Paracetamol is a mild analgesic and antipyretic, and is recommended for the treatment of most painful and febrile conditions, for example, headache including migraine, toothache, neuralgia, colds and influenza, sore throat, backache, rheumatic pain and dysmenorrhoea.
Acenocoumarol. Paracetamol increases the anticoagulant effect of Acenocoumarol. ...
Alcohol. Alcohol (in those who drink heavily) causes severe liver damage when given with Paracetamol. ...
Alectinib. ...
Asparaginase. ...
Atorvastatin. ...
Bedaquiline. ...
Busulfan. ...
Carbamazepine.
Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Store below 30°C
Do not panic. Unless your doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember it. Skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
Consult a doctor before taking any medicines.
Metacin 250mg Suppository is for use in children who find it difficult to take paracetamol as tablets or syrup.
This medicine is for rectal use only and should not be taken by mouth.
Never give any other medicine formulation containing paracetamol along with this medicine as that may lead to serious side effects.
Inform the doctor if your child has liver disease as the dose may need to be adjusted.
If Metacin 250mg Suppository does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.
Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Q. How should Metacin 250mg Suppository be used?
Metacin 250mg Suppository is meant to be placed inside the rectum (bottom area). It uses the body's heat and melts inside, resulting in direct absorption into the bloodstream and rendering quick relief. Use Metacin 250mg Suppository as directed by your child’s doctor. Before insertion, wash your hands properly. Guide your child to lie down sideways or on the belly. Hold one buttock gently to get access to the rectal area. Unwrap the medicine and hold the rounded end close to the rectum. Use one finger to gently push Metacin 250mg Suppository into the rectum. Ask your child to remain still for about 15 minutes as it will prevent the medicine from popping out. Clean your hands again with soap and water to ensure hygiene.
Q. How much Metacin 250mg Suppository should I give to my child?
It will depend on the strength of the medicine and the age of your child. Always follow your doctor's instructions regarding how much and how often the medicine should be given to your child. In case you are not sure about how much to give, consult your child’s doctor.
Q. Can I give Metacin 250mg Suppository to my child for low-grade fever?
You can give this medicine if your child has a temperature of 38.3°C (101°F) or higher. But, you must always try to speak to your child’s doctor first.
Q. My child’s fever is persistent even after taking Metacin 250mg Suppository. What should I do?
If the fever doesn't come down, the cause might be an infection (virus or bacteria). It is advised to consult your child’s doctor for specific treatment.
