Manufacturer: Lupin Ltd
Salt Composition : Metoclopramide(10mg), Magaldrate(480mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Metadrate Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are diarrhea, taste change, weakness, restlessness, and tremor. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney diseases so that your doctor can prescribe a suitable dose for you.
Metadrate Tablet is used to prevent nausea and vomiting due to various reasons. It speeds up the passage of food through the stomach into the intestine, which helps prevent vomiting. It also prevents food from flowing upwards.
Metoclopramide promotes gut motility by the following three mechanisms: inhibition of presynaptic and postsynaptic D2 receptors, stimulation of presynaptic excitatory 5-HT4 receptors and antagonism of presynaptic inhibition of muscarinic receptors (Figure 2A).Magaldrate is a hydroxymagnesium aluminate complex that is converted rapidly by gastric acid into Mg(OH)2 and Al(OH)3, which are absorbed poorly and thus provide a sustained antacid effect.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metadrate
Diarrhea
Taste change
Weakness
Sleepiness
Restlessness
Tremors
Parkinson-like symptoms
Depression
Hypersensitivity to Metadrate Tablet is a contraindication. In addition, Metadrate Tablet should not be used if you have the following conditions:
Abnormal movements of face muscles and tongue
Aldosteronism
Bleeding of the stomach or intestines
Chronic heart failure
Controlled magnesium diet
Deficiency of the blood enzyme cytochrome b5 reductase
Depression
Hardening of the liver
Having thoughts of suicide
High blood pressure
Information regarding the use of Metadrate Tablet during pregnancy is not available. Please consult your doctor.
It is unsafe to consume alcohol with Metadrate Tablet.
Metadrate Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Use with caution
Below 9years: Contraindicated
Metoclopramide+Magaldrate is used in the treatment of acidity and vomiting.Metoclopramide is a prokinetic which works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach. Magaldrate is an inorganic salt that neutralizes the excess acid in the stomach.
If you use other drugs or over the counter products at the same time, the effects of Metadrate Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Metadrate Tablet may interact with the following drugs and products:
Aspirin
Atovaquone
Atropine
Barium sulphate
Benorylate
Biperiden
Bromocriptine
Cabergoline
Chlordiazepoxide
Chlorothiazide
Do not chew, crush or break it. Metadrate Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Metadrate Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Metadrate Tablet helps relieve vomiting and acidity.
This medicine will only be prescribed for a short period (no more than five days) and your doctor may want to check on your progress afterwards.
Drink plenty of water while taking Metadrate Tablet.
Do not take Metadrate Tablet at least 2 hours before or after taking other medicines as it may interact with other medicines.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Incorporate the folowing lifestyle changes in order to prevent acidity:
Make sure you eat regular meals and drink plenty of water.
Avoid spicy and fatty fried food.
Lose weight if you are obese.
If you are a smoker, consider giving up.
Don't drink too much alcohol.
Do not go to bed immediately after taking a meal. Sit in a relaxed position for some time for better digestion.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metadrate Tablet is to be taken empty stomach.
