Metageston Depot 500mg Injection (2ml)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Metageston Depot 500mg Injection is generally given by a healthcare professional and should not be self-administered at home. You should use Metageston Depot 500mg Injection as your doctor has advised. Do not use more or less than advised and do not use it for longer than recommended. You may be asked to continue taking this medicine for a period after you get pregnant.

The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Your doctor may suggest ways to reduce or prevent these. Occasionally, it may cause a severe allergic reaction requiring urgent medical attention.

Inform your doctor if you have a history of breast cancer, unusual vaginal bleeding, or liver, kidney, or heart disease. Inform your doctor about all other medicines that you are taking as they may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment with this medicine. Metageston Depot 500mg Injection can alter your thinking or reactions and you may feel very tired so be careful while driving or doing anything that requires you to be alert.


Basic Information

Mechanism Of Action

This medicine replenishes the female hormone i.e. progesterone which is required for normal functioning of the uterus, menses and fertility.

Pharmacokinets

The pharmacokinetics of progesterone are dependent on its route of administration. The medication is approved in the form of oil-filled capsules containing micronized progesterone for oral administration, termed "oral micronized progesterone" ("OMP") or simply "oral progesterone".


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Progeston

Hot flushes

Severe side effects of Progeston

Abdominal pain

Sleepiness

Absence of menstrual periods

Itching

Flatulence

Nausea

Depression

Breast tenderness

Abnormal vaginal bleeding

Altered menstrual cycle

Edema (swelling)

Change in body weight

Changes in cervical secretion

Cholestatic jaundice

Injection site reactions (pain, swelling, redness)

Red spots or bumps

Acne

Hair loss

Excessive hair growth on face

Anaphylactic reaction

Fever

Insomnia (difficulty in sleeping)

Soreness

Diarrhea

Vaginal irritation

Vaginal dryness

Dementia

Deep vein thrombosis (blood clot in the legs)

Myocardial infarction

Stroke

Pulmonary embolism

Breast cancer

Contra Indications

Progesterone is contraindicated in patients with pre-existing breast cancer or cancer of reproductive organs, such as cervical cancer, endometrial cancer, ovarian cancer, uterine cancer, or vaginal cancer. Likewise, progesterone formulations should not be used in patients with undiagnosed vaginal bleeding.

Pregnancy Related Information

Metageston Depot 500mg Injection is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Metageston Depot 500mg Injection. Please consult your doctor.


Breast Feeding Related Information

Metageston Depot 500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Progesterone (Natural Micronized) is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in menstruating women). It is used to support pregnancy, prevent premature labor and treat bleeding disorders that may occur before menopause.

Interactions

bazedoxifene/conjugated estrogens.

conjugated estrogens.

conjugated estrogens, vaginal.

doxorubicin.

doxorubicin liposomal.

ruxolitinib.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Metageston Depot 500mg Injection, consult your doctor.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Metageston Depot 500mg Injection is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.

It is used as a part of hormone replacement therapy generally in combination with an estrogen.

It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).

It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.

It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. What is Metageston Depot 500mg Injection and what is it used for?

Metageston Depot 500mg Injection contains progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. It is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).

Q. How and in what dose should I take Metageston Depot 500mg Injection?

Metageston Depot 500mg Injection is given as an injection into the muscle, by a doctor or nurse only. The dose and duration are decided by your doctor, depending on your exact medical condition. Follow your doctor’s instructions carefully to get the maximum benefit from Metageston Depot 500mg Injection.

Q. What are the common side effects which I can experience while taking Metageston Depot 500mg Injection?

The common side effects associated with Metageston Depot 500mg Injection are local injection site reactions (redness, pain, or swelling), nausea, vaginal discharge, weight changes, jaundice, mental depression, and fever. If any of these side effects bother you, please consult with your doctor.

Q. Does Metageston Depot 500mg Injection cause weight gain?

Yes, the use of Metageston Depot 500mg Injection may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you.

Q. How is Metageston Depot 500mg Injection beneficial for fertility and pregnancy?

Metageston Depot 500mg Injection is a crucial hormone for fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. This is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent abortions in some cases. It is also used to prevent premature labor.

Q. Is Metageston Depot 500mg Injection effective?

Metageston Depot 500mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Metageston Depot 500mg Injection too early, the symptoms may return or worsen.