Manufacturer: Zydus Cadila
Salt Composition : Methotrexate(5mg)
Strip of 4 Tablet
(Inclusive of all taxes)
Mexate Tablet is used in the treatment of rheumatoid arthritis and psoriasis. It contains methotrexate as an active ingredient. You should never suggest this medicine to anyone, even if their condition is similar to yours. The doctor will decide the dosage and frequency of this medicine based on your clinical condition. You should take this medicine exactly as suggested by your doctor. Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding. Also inform about all the medicines and supplements you are taking and all the conditions or diseases you suffer from, before starting Mexate Tablet.
Mexate Tablet stops or reduces inflammation in rheumatoid arthritis by altering the body’s defenses.
In psoriasis, it kills the cells in the skin, which are growing too quickly. It is these fast growing cells, which cause the raised patches of skin in psoriasis.
Transport of MTX across the capillary and cell membranes of the liver, kidney, and skin is rapid, so that equilibrium ratios of tissue to plasma concentrations (plasma concentrations > 1 µM) are established on a time scale consistent with plasma flow limitation.
Stomach discomfort
Mouth ulcers
Nausea
Drowsiness
Muscle pain
If you are allergic to methotrexate or any of the ingredients of Mexate Tablet.
If you are pregnant or breastfeeding.
If you have any underlying medical conditions like liver or kidney disorders.
If you have low levels of white blood cells and platelets.
If you recently had an injection of live vaccines.
If you have mouth ulcers or ulcers in the stomach/intestine.
If you are an alcoholic.
Mexate Tablet is contraindicated for use in pregnancy. Women who are capable of becoming pregnant should use effective methods of birth control during treatment with Mexate Tablet.
No, the consumption of alcohol is contraindicated during treatment with Mexate Tablet.
Mexate Tablet is contraindicated for use in breastfeeding women.
Methotrexate is indicated in the management of selected adults with severe, active, rheumatoid arthritis (ACR criteria), or children with active polyarticular-course juvenile rheumatoid arthritis, who have had an insufficient therapeutic response to, or are intolerant of, an adequate trial of first-line therapy ...
Drug-Drug Interactions: METHOTREXATE may interact with pain killers (celecoxib, acetaminophen, hydrocodone), anti-depressant (duloxetine), immunosuppressants (etanercept), anti-rheumatoid (adalimumab), antacid (esomeprazole), and anti-malarial (hydroxychloroquine).
Drug-Food Interactions: Avoid consuming alcohol whilst on treatment with METHOTREXATE.
Drug-Disease Interactions: Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, or chronic liver disease.
Drug-Drug Interactions Checker List:
CELECOXIB
ACETAMINOPHEN
HYDROCODONE
DULOXETINE
ETANERCEPT
ADALIMUMAB
ESOMEPRAZOLE
HYDROXYCHLOROQUINE
Do not chew, crush or break it.
Store Mexate Tablet in a cool and dry place, away from direct sunlight.
Keep out of reach of children and pets.
If you have missed taking any dose of the Mexate Tablet, then take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one.
Symptoms of overdose of Mexate Tablet include nausea, vomiting, and mouth ulcers. If you think you have taken too much of Mexate Tablet, contact your doctor immediately or visit the nearest hospital.
You have any medical condition like blood disorder, kidney disorder, intestinal disorder, lung disease, a brain-related disorder.
You have mouth ulcers.
You have diabetes or are being treated with insulin.
Take Mexate Tablet as a whole with sufficient water.
Do not chew, crush or break it.
Always take this medicine exactly as prescribed by your doctor.
Do not consume more than the prescribed dose.
Q: What should I let my healthcare provider know before using Mexate Tablet?
A: It is advisable to inform your doctor about the complete medical history, any history of alcoholism and liver disorders due to alcoholism, immunodeficiency syndrome, anaemia, low count of white blood cells and low count of platelets before starting treatment with Mexate Tablet.
Q: How long will it take to feel better with the intake of Mexate Tablet?
A: It may take several months to experience the full benefit of Mexate Tablet until then do not stop or alter the course on your own.
