Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Imatinib mesylate(100mg)
Mitinab 100 mg Tablet shows side effects like skin rash, weight gain, diarrhoea, headache, loss of appetite, vomiting, stomach pain, and hair loss. Your hair grows back after the treatment and other side effects may subside on their own. If the side effects bother you or persist for a longer duration, consult your doctor. Do not perform activities that require mental alertness (such as driving or operating heavy machinery) after taking this medicine, as it may cause dizziness and drowsiness.
Mitinab 100 mg Tablet may be taken with a meal to avoid stomach irritation. Avoid drinking grapefruit juice with this medicine as it may increase the risk of side effects. Do not take more than the prescribed dose. The dosage and duration of this medicine are decided by your doctor based on the severity of your condition. Take this medicine at the same time every day to avoid any missed dose. In case of overdose consult your doctor immediately.
Mitinab 100 mg Tablet should not be used if you are allergic to it. Inform your doctor if you have kidney, liver, and heart diseases. Consult your doctor if you are pregnant, planning pregnancy, or are breastfeeding.
Mitinab 100 mg Tablet works by inhibiting the actions of certain substances (abnormal proteins) in your body that cause the cancer cells to multiply. This helps in stopping the growth and spread of cancer.
Imatinib, a 2-phenyl amino pyrimidine derivative, is a tyrosine kinase inhibitor with activity against ABL, BCR-ABL, PDGFRA, and c-KIT. The active sites of tyrosine kinases each have a binding site for ATP.
Major & minor side effects for Mitinab 100 mg Tablet
Diarrhea
Nausea and Vomiting
Mouth sores
Loss of appetite
Altered sense of taste
Heartburn and indigestion
Joint pain, stiffness, and swelling
Burning or tingling sensation of hands and feet
Trouble sleeping
Skin Rash
Hair loss
Swelling or the hands, feet, ankle, and lower legs
Shortness of breath
Fast/irregular heart beat
Unusual bleeding or bruising
Stomach pain
Headache
Dizziness
Drowsiness
Low blood count
There are no contraindications for imatinib. Administration of imatinib with CYP3A4 inducers may reduce total imatinib exposure. Administration of imatinib with CYP3A4 inhibitors may increase total imatinib exposure. Avoid grapefruit juice as it can potentially increase the plasma concentration of imatinib.
Mitinab 100 mg Tablet is not recommended for use during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant or planning a pregnancy.
Mitinab 100 mg Tablet is not recommended if you are breastfeeding as limited data is available. Consult your doctor if you are breastfeeding.
This medication is used to treat certain types of cancer (such as acute lymphoblastic leukemia, chronic myeloid leukemia, gastrointestinal stromal tumors, and myelodysplastic/myeloproliferative diseases). It works by slowing or stopping the growth of cancer cells.
Drug-Drug Interaction: IMATINIB is known to interact with blood thinners (warfarin, aspirin), anti-hypertensive medicines (amlodipine, metoprolol, nifedipine), heart medicines (quinidine, atorvastatin, lovastatin, simvastatin), immuno-suppressants (cyclosporine), antibiotics (erythromycin, telithromycin), anti-fungal medicines (itraconazole, voriconazole, ketoconazole), mental illness medicines (triazolam, alprazolam, estazolam, primidone, phenobarbital, phenytoin), anti-HIV medicines (saquinavir, ritonavir), erectile dysfunction medicine (sildenafil).
Drug-Food Interaction: IMATINIB is known to interact with alcohol, St. John's wort plant (a natural remedy to treat depression), and grapefruit.
Drug-Disease Interaction: Inform your doctor if you have hypothyroidism (underactive thyroid), cardiovascular disease, bone marrow suppression, liver or kidney disease, fluid retention, gastrointestinal disorders, stomach ulcer or bleeding, high blood pressure, diabetes or chemotherapy.
Drug-Drug Interactions Checker List:
WARFARIN
ASPIRIN
AMLODIPINE
METOPROLOL
NIFEDIPINE
QUINIDINE
ATORVASTATIN
LOVASTATIN
SIMVASTATIN
CYCLOSPORINE
ERYTHROMYCIN
TELITHROMYCIN
ITRACONAZOLE
VORICONAZOLE
KETOCONAZOLE
TRIAZOLAM
ALPRAZOLAM
ESTAZOLAM
PRIMIDONE
PHENOBARBITAL
PHENYTOIN
SAQUINAVIR
RITONAVIR
SILDENAFIL
Store below 30°C
Take the missed dose as soon as you remember. If it is time for the next scheduled dose, then skip the missed dose. Contact your doctor for further instructions if you miss more than one scheduled dose of this medicine.
Never take more than the prescribed dose. Contact your doctor or seek immediate medical attention if an overdose with this medicine is suspected.
Take Mitinab 100 mg Tablet with a meal to avoid stomach irritation
Take Mitinab 100 mg Tablet exactly as prescribed by your doctor. Avoid taking this medicine in larger or smaller quantities than recommended. Avoid the discontinuaton of this medicine without consulting your doctor.
You may require frequent blood tests and liver function tests while taking this medicine.
You may also require frequent follow-ups with your doctor to check the progress of treatment.
Avoid the exposure to direct sunlight. Use protective clothing and sunscreen while going out in the sun.
Blood cancer
Blood cancer occurs when abnormal blood cells start growing uncontrollably. This cancer starts in the bone marrow, a tissue in the bone where blood cells are produced. Mitinab 100 mg Tablet is used in the treatment of various types of blood cancers.
Dermatofibrosarcoma protuberans
Dermatofibrosarcoma protuberans is a skin cancer that begins in the middle layer of your skin. The cells grows and forms a lump on the surface of your skin. Mitinab 100 mg Tablet is used to treat this skin cancer.
Gastrointestinal stromal tumor
Mitinab 100 mg Tablet is used to treat gastrointestinal stromal tumour, cancer that starts in the walls of your stomach and intestine.
How long does it take for this medicine to take effect?
The amount of time taken by Mitinab 100 mg Tablet to show its effect is is not clinically established.
How long do the effects of this medicine last?
The amount of time for which Mitinab 100 mg Tablet remains effective in your body is not known.
Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Is this a habit forming medicine?
No habit-forming tendency was reported for Mitinab 100 mg Tablet
