Manufacturer: Claris Lifesciences Ltd
Salt Composition : Mycophenolate mofetil(500mg)
When our body encounters a foreign substance (bacteria, virus, fungus, transplanted organs or grafts), the immune system attacks it to protect the body. Normally this defence mechanism helps us, but in cases of organ transplant, the transplanted organ is also identified as a foreign body by our immunity and is attacked by it. Mygraft Tablet is given to such patients as it suppresses the immune response and prevents rejection of a kidney, liver or heart transplant or graft.
Mycophenolate mofetil is rapidly absorbed in the small intestine. The maximum concentration of its active metabolite, MPA, is attained 60 to 90 minutes following an oral dose. The average bioavailability of orally administered mycophenolate mofetil in a pharmacokinetic study of 12 healthy patients was 94%.
Acne
Rash
Gout
Depression
Insomnia
Dizziness
Headache
Cough
Abdominal pain
Bacterial infections
Anaemia
Contraindicated in patients with a hypersensitivity to mycophenolate mofetil, mycophenolic acid or any component of the drug product. With other immunosuppressive treatments, patients treated with mycophenolate are at increased risk of developing lymphomas, and other malignancies, particularly of the skin.
Do not take Mygraft Tablet if you are pregnant or planning to get pregnant as it will harm the developing baby and can even cause miscarriage. Discuss with your doctor about effective methods of contraception to be followed while taking this medicine.
Alcohol is not known to interact with this medicine. However, if you consume alcohol too often, discuss it with your doctor.
You should not breastfeed your baby if you are taking Mygraft Tablet as it may harm the baby. You should discuss about safer alternatives with your doctor in case breastfeeding has to be continued.
Mycophenolate mofetil is indicated in combination with other immunosuppressants to prevent the rejection of kidney, heart, or liver transplants in adult and pediatric patients ≥3 months old.
Drug-Drug interactions: MYCOPHENOLATE MOFETIL may interact with an immunosuppressant (azathioprine), antiviral medications (aciclovir and ganciclovir), a medication used to treat tuberculosis (rifampicin), antacids such as proton pump inhibitors, medications used to treat chronic kidney failure such as phosphate binders, and an antibiotic (norfloxacin+metronidazole).
Drug-Dood interactions: Avoid alcohol consumption as it may worsen the condition by increasing the risk of side effects.
Drug-Disease interactions: MYCOPHENOLATE MOFETIL should be used with caution in patients with liver or kidney disease, stomach ulcers, chronic infections and phenylketonuria.
Drug-Drug Interactions Checker List:
AZATHIOPRINE
ACICLOVIR
GANCICLOVIR
RIFAMPICIN
NORFLOXACIN+METRONIDAZOLE
Store at a temperature below 30º C in a cool and dry place.
Keep it out of the reach of children and pets.
If you have missed to take any dose of this medicine, then take it as soon as you remember. If it's already time for the next dose, then skip the missed dose and follow the regular dosing schedule.
If you have taken too much of this medicine, then contact your doctor or reach out to the nearest hospital immediately.
You are pregnant or planning to get pregnant or a nursing mother.
You are a man who is planning to become father or donate sperms.
You are diabetic.
You have high or low blood pressure.
You have stomach or intestinal ulcers or bleeding problems.
You have any viral, bacterial or fungal infection.
You have experienced any unusual bleeding or bluish spots on skin.
Avoid direct sunlight, use sunscreen and protective clothing and sunglasses.
Discuss your complete medical history with the doctor.
Take this medicine as prescribed by your doctor.
Q: How should I take Mygraft Tablet?
A: Take Mygraft Tablet as prescribed by your doctor and follow all instructions given by him. Inform your doctor in case you experience any unusual symptoms after starting this medicine - fever, rashes, unusual bleeding or bluish spots on the skin.
Q: How can I avoid skin related side effects with Mygraft Tablet?
A: Avoid exposure to direct sunlight. Wear protective clothing and sunglasses. Use good sunscreen.
