Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Levosulpiride(75mg), Rabeprazole(20mg)
Neopride Total Capsule SR is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, stomach pain, diarrhea, flatulence, constipation, headache, weakness, and flu-like symptoms. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.
Lifestyle modifications like having fiber-rich diet, avoiding foods that trigger your symptoms, increasing fluid intake and regular exercise can help you to get better results. Before taking it, you should tell your doctor if you have any kidney or liver diseases. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Rabeprazole works by blocking the secretion of acid in the stomach by acting on a pump called the proton pump in the stomach, responsible for the secretion of stomach acids. Levosulpiride works by increasing the motility of the stomach and intestine so that acid does not reflux back into the food pipe.
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Findings: Levosulpiride exhibited linear pharmacokinetic properties over the dose range of 25 to 100 mg by PO route and 25 to 75 mg by IM route. The corresponding mean AUC0-t increased from 449 to 1443 ng/h/mL and from 2874 to 7559 ng/h/mL, respectively.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Neopride Total
Nausea
Stomach pain
Diarrhea
Flatulence
Constipation
Headache
Dizziness
Weakness
Sleepiness
Flu-like symptoms
If you are allergic to levosulpiride, rabeprazole or similar medicines.
If you are pregnant or breastfeeding.
If you have a history of fits or Parkinson's disease.
Neopride Total Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Neopride Total Capsule SR.
Information regarding the use of Neopride Total Capsule SR during breastfeeding is not available. Please consult your doctor.
LEVOSULPIRIDE+RABEPRAZOLE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers.
Drug-Drug Interactions: LEVOSULPIRIDE+RABEPRAZOLE may interact with a blood thinner (warfarin), anti-cancer (methotrexate), cardiac glycoside (digoxin), immunosuppressant (mycophenolate mofetil, tacrolimus), antibiotic (amoxicillin, clarithromycin). Drug-Food Interactions: No interactions found/established.
Do not chew, crush or break it. Neopride Total Capsule SR is to be taken empty stomach.
Store below 30°C
If you miss a dose of Neopride Total Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
It is a well-tolerated medicine and provides relief for a long time.
Take it one hour before the meal, preferably in the morning.
Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Do not consume alcohol while taking Neopride Total Capsule SR as it can increase the risk of stomach damage.
Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take Neopride Total Capsule SR for longer than prescribed.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neopride Total Capsule SR is to be taken empty stomach.
Q. Which is the best time to take Neopride Total Capsule SR?
Take the Neopride Total Capsule SR exactly as directed by your doctor. It is best to take one capsule daily on an empty stomach.
Q. What are the contraindications associated with the use of Neopride Total Capsule SR?
Use of Neopride Total Capsule SR should be avoided in patients with known allergy to any of the components or excipients of this medicine.
Q. Can the use of Neopride Total Capsule SR cause dizziness?
Yes, the use of Neopride Total Capsule SR can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.
Q. Does the use of Neopride Total Capsule SR lead to increased risk of fractures?
Several studies in adults suggest that treatment with Neopride Total Capsule SR may be associated with an increased risk of osteoporosis-related fractures of the hip, wrist or spine. The risk of fracture was increased in patients who received high dose. High dose can mean multiple daily doses, and long-term therapy (a year or longer).
