Neuronox 100IU (Injection)


Neuronox 100IU Injection is a prescription medicine that must be administered by a healthcare professional. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.


The common side effects of this medicine are injection site pain, tiredness, Eye dryness, difficulty in swallowing, bruising, and skin rash. It may also cause injection site reactions such as redness, pain, and swelling in some people. The medicine can safely be used in children.


Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment.


Basic Information

Mechanism Of Action

Neuronox 100IU Injection is a protein made by a type of bacteria (Clostridium botulinum type A). It works by blocking the release of a chemical (acetylcholine). This temporarily weakens nerve activity in the muscles around your bladder and relieves symptoms such as urinary urgency and frequency. It also blocks pain signals in migraine and treats various types of involuntary muscle contractions.

Pharmacokinets

Based on preclinical studies, onabotulinumtoxinA is known to inhibit the release of excitatory neurotransmitters from both motor and sensory neurons by preventing vesicle fusion to the cell membrane.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neuronox

Injection site reactions (pain, swelling, redness)

Injection site pain

Pain in extremities

Upper respiratory tract infection

Flu-like symptoms

Dry eye

Abnormal bruising

Skin rash

Contra Indications

Infection at injection site(s)

UTI during bladder treatment.

Trouble urinating and not using a catheter during bladder treatment regularly.

Pregnancy Related Information

Neuronox 100IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Neuronox 100IU Injection. Please consult your doctor.

Breast Feeding Related Information

Neuronox 100IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Indications

Overactive Bladder (onabotulinumtoxinA) for injection is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency, in adults who have an inadequate response to or are intolerant of an anticholinergic medication.

Interactions

Some products that may interact with this drug include: certain antibiotics (including aminoglycosides such as gentamicin, polymyxin), anticoagulants (such as warfarin), Alzheimer's disease drugs (such as galantamine, rivastigmine, tacrine), myasthenia gravis drugs (such as ambenonium, pyridostigmine), quinidine.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Neuronox 100IU Injection prevents headaches in people with chronic migraines and treats various other problems such as muscle spasms and wrinkles.

It can prevent migraines before they even start.

Your doctor will give you many injections spread over different sites, depending on your condition.

It may cause swallowing, speaking, or breathing problems. Inform your doctor if you develop trouble swallowing, slurred speech, loss of bladder control, muscle weakness or breathing difficulties.

It may cause dizziness. Don't drive or do anything requiring concentration until you know how it affects you.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. Can I use Neuronox 100IU Injection for lower limb spasticity?

Yes, Neuronox 100IU Injection is used to treat lower limb spasticity (stiffness or increased muscle tone) in adult patients to decrease the severity of increased muscle tone in ankle and toe.

Q. Can I use Neuronox 100IU Injection for cosmetic reasons?

Yes, Neuronox 100IU Injection can be used for cosmetic reasons in adults aged 18 years or more. These cosmetic uses may include temporary smoothening of frown lines (wrinkles between the eyebrows), crow's feet lines (wrinkles near the outer corner of the eye), and forehead lines.

Q. How long can I take Neuronox 100IU Injection?

The duration will depend upon the condition for which Neuronox 100IU Injection is being prescribed for. It is generally given as a one-time injection. The injection can be repeated after 3 months or 6-7 months, as advised by our doctor.

Q. Can Neuronox 100IU Injection worsen migraine?

No, in fact Neuronox 100IU Injection is used to prevent headaches in adults with chronic migraine. It is especially used in adults who have 15 or more days each month with headache lasting 4 or more hours each day.