Manufacturer: Torrent Pharmaceuticals Ltd
Salt Composition : Levosulpiride(75mg), Esomeprazole(40mg)
Strip of 10 Capsule Dr
(Inclusive of all taxes)
Nexpro L Capsule ER is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are diarrhea, nausea, vomiting, stomach pain, flatulence, constipation, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. To overcome constipation, you should add fibre-rich foods in your diet and stay hydrated. It may also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver or kidney diseases so that your doctor can prescribe a suitable dose for you.
Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, ESOMEPRAZOLE+LEVOSULPIRIDE helps in preventing acid reflux, thereby providing relief from acidity.
Esomeprazole is extensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system. The major part of esomeprazole's metabolism is dependent upon the CYP2C19 isoenzyme, which forms the hydroxy and desmethyl metabolites. The remaining amount is dependent on CYP3A4 which forms the sulphone metabolite.
Levosulpiride exhibited linear pharmacokinetic properties over the dose range of 25 to 100 mg by PO route and 25 to 75 mg by IM route. The corresponding mean AUC0-t increased from 449 to 1443 ng/h/mL and from 2874 to 7559 ng/h/mL, respectively.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nexpro L
Nausea
Vomiting
Diarrhea
Constipation
Upset stomach
Stomach pain
Headache
Flatulence
Sleepiness
If you have allergic to levosulpiride or similar medicines.
If you have any psychiatric disorder such as fits, sudden change in mood.
If you are pregnant or breastfeeding.
If you are suffering from changes in breast tissues and nodules and have a high level of prolactin hormone.
Nexpro L Capsule ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Nexpro L Capsule ER.
Information regarding the use of Nexpro L Capsule ER during breastfeeding is not available. Please consult your doctor.
ESOMEPRAZOLE+LEVOSULPIRIDE belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn.
Drug-Drug Interactions: ESOMEPRAZOLE+LEVOSULPIRIDE may interact with painkillers (aspirin, naproxen), anti-HIV (atazanavir), blood thinner (clopidogrel, warfarin, cilostazol), anti-fungal (ketoconazole, itraconazole, voriconazole), anti-cancer (erlotinib, methotrexate), anti-depressant (citalopram, imipramine
Do not chew, crush or break it. Nexpro L Capsule ER is to be taken empty stomach.
Store below 30°C
If you miss a dose of Nexpro L Capsule ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
It is a well-tolerated medicine and provides relief for a long time.
Take it one hour before the meal, preferably in the morning.
Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Do not consume alcohol while taking Nexpro L Capsule ER as it can increase the risk of stomach damage.
Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take Nexpro L Capsule ER for longer than prescribed.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nexpro L Capsule ER is to be taken empty stomach.
Q. What are the instructions for storage and disposal of Nexpro L Capsule ER?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What is the best time to take Nexpro L Capsule ER?
Take Nexpro L Capsule ER exactly as directed by your doctor. It is best to take one capsule daily on an empty stomach.
Q. What are the contraindications associated with the use of Nexpro L Capsule ER?
The use of Nexpro L Capsule ER should be avoided in patients with known allergy to any of the components or excipients of this medicine.
Q. Can the use of Nexpro L Capsule ER cause dizziness?
Yes, the use of Nexpro L Capsule ER can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
