Manufacturer: Abbott
Salt Composition : Aceclofenac(100mg), Paracetamol(325mg), Chlorzoxazone(250mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Nicoace MR Tablet can be taken with or without food. The dose and duration will depend on the severity of your condition. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it.
Using this medicine may cause common side effects such as nausea, vomiting, heartburn, stomach pain, diarrhea, and loss of appetite. If these persist or get worse, let your doctor know. In general, you should try to use the smallest amount necessary to control your symptoms.
Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. To make sure it is safe, you should let your doctor know all the other medicines you are taking. Also, tell your doctor if you have any problems with the liver or kidneys. You should avoid the consumption of alcohol while on treatment with this medicine. Pregnant and breastfeeding women should consult their doctors first before using the medicine.
Nicoace MR Tablet is a combination of two pain relieving medicines (Aceclofenac and Paracetamol) and a muscle relaxant (Chlorzoxazone). The pain relieving medicines work by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). The muscle relaxant works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm, thereby improving muscle movement.
Aceclofenac potently inhibits the cyclo-oxygenase enzyme (COX) that is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and fever. Aceclofenac belongs to BCS Class II as it possesses poor aqueous solubility 2. Paracetamol is also well absorbed from the rectum. It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Chlorzoxazone is rapidly metabolized in the liver and is excreted in the urine, primarily in a conjugated form as the glucuronide. Chlorzoxazone is rapidly metabolized and is excreted in the urine, primarily in a conjugated form as the glucuronide.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nicoace MR
Nausea
Vomiting
Heartburn
Stomach pain
Diarrhea
Loss of appetite
Tiredness
Sleepiness
If you are experiencing bleeding from stomach and intestine or have an active peptic ulcer.
If you are allergic to other painkillers such as aspirin and have experienced severe asthma, rashes or any other allergy.
If you are suffering from any heart disease like heart failure and high blood pressure.
If you have problems with kidney and liver function.
If you are pregnant or elderly (65 years of age or older).
Information regarding the use of Nicoace MR Tablet during pregnancy is not available. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Nicoace MR Tablet. Please consult your doctor.
Information regarding the use of Nicoace MR Tablet during breastfeeding is not available. Please consult your doctor.
Aceclofenac+Paracetamol+Chlorzoxazone is a combination of three medicines: Aceclofenac, Paracetamol and Chlorzoxazone. This medicine helps in relieving muscle pain by relaxing the affected muscles. It relieves pain caused due to muscle spasm, cramp or injury.
Drug-Drug Interactions: ACECLOFENAC+PARACETAMOL+CHLORZOXAZONE interacts with sleeping pills (alprazolam, escitalopram, zolpidem), pain killers (tramadol, oxycodone, hydrocodone), antiepileptics or medicines for fits (gabapentin, topiramate, pregabalin), diuretics or water pills (fluoxetine), an antidepressant (duloxetine), antiallergic (diphenhydramine, cetirizine), muscle relaxant and antispasmodic (baclofen).
Drug-Food Interactions: St. John's wort (a herbal supplement) used as an antidepressant can interact with ACECLOFENAC+PARACETAMOL+CHLORZOXAZONE and cause dizziness, so its usage should be avoided with ACECLOFENAC+PARACETAMOL+CHLORZOXAZONE.
Drug-Disease Interactions: People with alcoholism, liver disease, kidney disease, stomach ulcer/bleeding, and intestinal ulcer/bleeding should avoid using ACECLOFENAC+PARACETAMOL+CHLORZOXAZONE.
Do not chew, crush or break it. Nicoace MR Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Nicoace MR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Avoid consuming alcohol when taking Nicoace MR Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Older adults may have increased drowsiness, confusion, and higher risk of falling as a result of taking Nicoace MR Tablet.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nicoace MR Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Nicoace MR Tablet?
Nicoace MR Tablet is a combination of three medicines: Aceclofenac, Paracetamol and Chlorzoxazone. This medicine helps in relieving muscle pain by relaxing the affected muscles. It relieves pain caused due to muscle spasm, cramp or injury. It also lowers certain chemical substances in the body that cause pain.
Q. What can I do along with Nicoace MR Tablet to reduce muscle pain?
If you are suffering from muscle pain due to muscle injury or overuse, you should take rest. Taking rest will help you avoid any further injury and help you recover efficiently. Make sure that you take plenty of sleep and try to reduce stress. Applying ice pack to the affected area may help in relieving pain and inflammation. If your muscle pain is due to some other disease, follow the advice of your doctor.
Q. Can I get addicted to Nicoace MR Tablet?
No, there are no reports of any patient getting addicted to Nicoace MR Tablet.
Q. Can I stop taking Nicoace MR Tablet when my pain is relieved?
Nicoace MR Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Nicoace MR Tablet should be continued if you are advised by your doctor to do so.
