Manufacturer: Torrent Pharmaceuticals Ltd
Salt Composition : Nicorandil(48mg)
Vial of 20ml Injection
(Inclusive of all taxes)
Nikoran IV 48 Injection is administered under the supervision of a healthcare professional and should not be self administered. Your doctor will decide the dose and how often you should take them. Your doctor is likely to prescribe you oral medicines after the treatment with this medicine. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking exercising regularly and managing stress.
The most common side effect of this medicine is headache, especially during the first few days of treatment. You can reduce this by drinking plenty of fluids and avoiding alcohol, but it usually goes after a week. Other common side effects include ulcer, feeling dizzy or weak, nausea and vomiting, palpitation, and flushing (sense of warmth in the face, ears, neck and trunk). Talk to your doctor if these bother you or do not go away.
Nikoran IV 48 Injection is not suitable for some people. Tell your doctor if you have low blood pressure, a problem with fluid in your lungs or kidney problems. Also let your healthcare team know all other medications you are using as some may affect, or be affected by this medicine. You should not take any medicines for erectile dysfunction with this medicine. This medicine is not usually recommended during pregnancy or breastfeeding. Drinking alcohol can increase the blood pressure-lowering effect of Nikoran IV 48 Injection. Your doctor may ask you to avoid salt substitutes.
Nikoran IV 48 Injection is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. This reduces the frequency and severity of angina attacks.
Nicorandil pharmacokinetics are linear from 5 mg to 40 mg. After oral administration, nicorandil is absorbed rapidly and completely from the gastrointestinal tract, independent from food intake. The absolute bioavailability is about 75%. There is no significant hepatic first pass effect.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nikoran
Headache
Ulcer
Dizziness
Weakness
Nausea
Vomiting
Palpitations
Flushing (sense of warmth in the face, ears, neck and trunk)
ever had an allergic reaction to nicorandil or any other medicine.
low blood pressure (hypotension)
a problem with fluid build-up in the lungs (pulmonary oedema)
recently had a heart attack or been told you have heart failure.
Nikoran IV 48 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Nikoran IV 48 Injection.
Information regarding the use of Nikoran IV 48 Injection during breastfeeding is not available. Please consult your doctor.
Nicorandil is indicated in adults for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled or have a contraindication or intolerance to first-line antianginal therapies (such as beta-blockers and/or calcium antagonists).
Nicorandil may increase the hypotensive activities of Acebutolol. The therapeutic efficacy of Nicorandil can be decreased when used in combination with Aceclofenac. The therapeutic efficacy of Nicorandil can be decreased when used in combination with Acemetacin.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Nikoran IV 48 Injection, consult your doctor.
Consult a doctor before taking any medicines.
You must continue to take it as advised, usually for a long time.
Nikoran IV 48 Injection may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
Nikoran IV 48 Injection may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.
Do not consume alcohol while taking Nikoran IV 48 Injection as that may cause increased dizziness.
Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Nikoran IV 48 Injection as it may cause low blood pressure.
Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is Nikoran IV 48 Injection and what is it used for?
Nikoran IV 48 Injection belongs to a class of medicines known as potassium channel openers. It helps in the removal of potassium from the walls of arteries resulting in widening of the arteries. This decreases the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients of stable angina (heart-related chest pain) who cannot take other medicines (beta blockers, calcium channel antagonist) meant for angina.
Q. How long does it take Nikoran IV 48 Injection to start working?
Nikoran IV 48 Injection starts working after about an hour of taking the medicine, but full benefits may be seen only after 4 to 5 days.
Q. What if somebody accidentally takes excess of Nikoran IV 48 Injection?
He or she should be taken to the hospital immediately. The person may experience signs of low blood pressure, which include feeling weak or dizzy. He or she may also experience irregular or fast heart beat.
Q. Can I take Nikoran IV 48 Injection if I am taking aspirin?
You should avoid taking Nikoran IV 48 Injection and aspirin together. Taking these two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor, If you notice blood in your stool or vomit while using Nikoran IV 48 Injection.
