Manufacturer: Modi Mundi Pharma Pvt Ltd
Salt Composition : Nitroglycerin(6.4mg)
Nitrocontin 6.4 Tablet CR should be taken in the dose and duration as advised by your doctor. It may be taken with or without food, preferably at a fixed time each day. Do not consume more than the recommended dose, as this may have harmful effects on your body. You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
The most common side effect of this medicine is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Do not use this medicine if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), erectile dysfunction or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, planning to become pregnant, or breastfeeding, ask your doctor before taking this medicine.
As with other nitrates used to treat anginal chest pain, nitroglycerin converts to nitric oxide (NO) in the body. NO then activates the enzyme guanylyl cyclase, which converts guanosine triphosphate (GTP) to guanosine 3',5'-monophosphate (cGMP) in vascular smooth muscle and other tissues.
Pharmacokinetics and Drug Metabolism Absorption: Nitroglycerin is rapidly absorbed following sublingual administration of Nitrostat tablets. Mean peak nitroglycerin plasma concentrations occur at a mean time of approximately 6 to 7 minutes postdose (Table 1).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nitrocontin
Blurred vision
Decreased blood pressure
Dizziness
Headache
Increased heart rate
Lightheadedness
Paresthesia (tingling or pricking sensation)
Nitroglycerin is contraindicated in patients that have reported allergic symptoms to the medication. Known history of increased intracranial pressure, severe anemia, right-sided myocardial infarction, or hypersensitivity to nitroglycerin are contraindications to nitroglycerin therapy.
Nitrocontin 6.4 Tablet CR is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol while taking Nitrocontin 6.4 Tablet CR may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Nitrocontin 6.4 Tablet CR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring.
Nitroglycerin may interact with certain other medications, such as PDE-5 inhibitors. PDE-5 inhibitors are drugs that doctors give to treat erectile dysfunction. Viagra, Cialis, and Levitra are PDE-5 inhibitors. As with nitroglycerin, these drugs also cause increased blood flow and can lower blood pressure.
Do not chew, crush or break it. Nitrocontin 6.4 Tablet CR may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Nitrocontin 6.4 Tablet CR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Nitrocontin 6.4 Tablet CR may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Nitrocontin 6.4 Tablet CR as it may cause increased dizziness.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
You may develop tolerance to Nitrocontin 6.4 Tablet CR with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrocontin 6.4 Tablet CR as it may cause low blood pressure.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nitrocontin 6.4 Tablet CR may be taken with or without food, but it is better to take it at a fixed time.
Q. Can I take sildenafil if I am taking Nitrocontin 6.4 Tablet CR?
No, you should not take sildenafil if you are taking Nitrocontin 6.4 Tablet CR. Taking these two medicines together can cause an excessive fall in blood pressure, which may even be life-threatening.
Q. What effect does Nitrocontin 6.4 Tablet CR have on blood pressure?
Nitrocontin 6.4 Tablet CR decreases the blood pressure by relaxing the blood vessels, but is not recommended for the treatment of high blood pressure. The drop in blood pressure may cause lightheadedness, especially when changing your position suddenly.
Q. Does the effect of Nitrocontin 6.4 Tablet CR wear off after some time?
Yes, excessive use of Nitrocontin 6.4 Tablet CR may cause tolerance which means that Nitrocontin 6.4 Tablet CR may lose its effectiveness on you. Therefore, usually the doctors prescribe the smallest dose required for effective relief of acute angina attack. This helps maintain the effectiveness of Nitrocontin 6.4 Tablet CR.
Q. What does too much Nitrocontin 6.4 Tablet CR do?
Excess Nitrocontin 6.4 Tablet CR may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.