Manufacturer: Vhb Life Sciences Inc
Salt Composition : Nitroglycerin(50mg)
Ampoule of 5ml Injection
(Inclusive of all taxes)
Nitrovir 50mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind.
The most common side effect of Nitrovir 50mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Do not use Nitrovir 50mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.
As with other nitrates used to treat anginal chest pain, nitroglycerin converts to nitric oxide (NO) in the body. NO then activates the enzyme guanylyl cyclase, which converts guanosine triphosphate (GTP) to guanosine 3',5'-monophosphate (cGMP) in vascular smooth muscle and other tissues.
Pharmacokinetics and Drug Metabolism Absorption: Nitroglycerin is rapidly absorbed following sublingual administration of Nitrostat tablets. Mean peak nitroglycerin plasma concentrations occur at a mean time of approximately 6 to 7 minutes postdose (Table 1).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nitrovir
Blurred vision
Decreased blood pressure
Dizziness
Headache
Increased heart rate
Lightheadedness
Paresthesia (tingling or pricking sensation)
Nitroglycerin is contraindicated in patients that have reported allergic symptoms to the medication. Known history of increased intracranial pressure, severe anemia, right-sided myocardial infarction, or hypersensitivity to nitroglycerin are contraindications to nitroglycerin therapy.
Nitrovir 50mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol while taking Nitrovir 50mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Nitrovir 50mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring.
Nitroglycerin may interact with certain other medications, such as PDE-5 inhibitors. PDE-5 inhibitors are drugs that doctors give to treat erectile dysfunction. Viagra, Cialis, and Levitra are PDE-5 inhibitors. As with nitroglycerin, these drugs also cause increased blood flow and can lower blood pressure.
Kindly do not self administer.
Store below 30°C
It is given via a drip into a vein under the supervision of a doctor.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
Nitrovir 50mg Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Nitrovir 50mg Injection as it may cause increased dizziness.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrovir 50mg Injection as it may cause low blood pressure.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Does the effect of Nitrovir 50mg Injection wear off after sometime?
Yes, excessive use of Nitrovir 50mg Injection may cause tolerance which means that Nitrovir 50mg Injection may lose its effectiveness on you. Therefore, doctors usually prescribe the smallest dose required for effective relief of acute angina attacks. Also, it is usually prescribed in morning and afternoon doses to give nitrate-free interval. Take it strictly as per the dosing interval prescribed by your doctor to prevent tolerance and maintain the effectiveness of Nitrovir 50mg Injection.
Q. What effect does Nitrovir 50mg Injection have on blood pressure?
Nitrovir 50mg Injection slightly decreases the blood pressure by relaxing the blood vessels, but is not recommended for the treatment of high blood pressure. The drop in blood pressure may cause lightheadedness, especially when changing your position suddenly. You should avoid sudden change in your position, for eg, get up slowly if you are sitting or lying down, to minimise this side effect.
Q. What does too much Nitrovir 50mg Injection do?
Excess Nitrovir 50mg Injection may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.
Q. Does Nitrovir 50mg Injection stop heart attacks?
Nitrovir 50mg Injection is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease, the blood vessels (coronary arteries) which supply blood to the heart become narrow because of which the heart has to work harder to get enough oxygen. Nitrovir 50mg Injection prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.
