Manufacturer: AstraZeneca
Salt Composition : Tamoxifen(10mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Breast cancer is a disease in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer.
Along with this treatment, your doctor might ask you to make certain lifestyle changes such as eating a healthy diet, healthy sleep habits and managing your weight. Prior to the treatment, your doctor may want you to take certain breast examinations to understand your existing condition.
NOLVADEX is not recommended for use in patients with a history of blood clots (including family), taking treatment for infertility.
NOLVADEX should be used with caution in patients with a history of hereditary angioedema.
NOLVADEX is not recommended for use in pregnant women. Inform your doctor before taking NOLVADEX if you are breastfeeding.
NOLVADEX is not recommended for use in children. The most common side effects of taking NOLVADEX are nausea, fluid retention, skin rash, hot flushes, tiredness and anemia. Consult your doctor if any of the above side effects worsen or persist for a long time.
NOLVADEX works by binding to estrogen receptors and blocking the effects of estrogen (natural female hormone) in the breast tissue. This slows down the growth and multiplication of breast cancer cells.
Tamoxifen typically has an elimination half-life of 5–7 days. The half-life of endoxifen ranges from 49.0 to 68.1 h for doses ranging from 20 and 160 mg. Tamoxifen has a prolonged Tmax of 4–7 h, and endoxifen has a shorter Tmax of 2–4 h.
SIDE EFFECTS OF NOLVADEX
COMMON
Nausea, vomiting
Fluid retention
Skin rash
Hot flushes (feeling of warmth)
Tiredness
Anemia
Changes in vision due to cataracts or changes to the retina of eye
Increased amounts of fats in your blood
Allergic reactions
Leg cramps
Changes in the womb (including changes to its lining and benign growths)
Headache, light-headedness
Itching of the genitals
Thinning of the hair
Diarrhea
Constipation
Changes in blood tests of liver function
Formation of fatty liver cells
Muscle pain
Sensory changes
Increased risk of blood clots
UNCOMMON
Blood problems
Changes in vision and difficulty seeing
Swelling of the pancreas
Changes in the amount of calcium in your blood
Inflammation of the lungs
RARE
Changes in the cornea of eye
Problems with the nerve that connects retina to your brain
Swelling of the optic nerve
Damage to blood vessels causing reddish or purplish dots on the skin
Severe skin disorder (redness, blistering and peeling)
Non-cancerous mass in inner lining of vagina
Worsening of the symptoms of breast cancer such as an increase in pain and/or an increase in the size of the affected tissue may occur
You should not take tamoxifen if you have a history of blood clots or take blood-thinning medicine. Tamoxifen increases the risk of blood clots. You should not take tamoxifen if you are breastfeeding, pregnant, trying to get pregnant, or if there is any chance that you could be pregnant.
NOLVADEX is not recommended for use in pregnant women. Consult your doctor immediately if you think you may have become pregnant after starting the treatment.
Inform your doctor if you are breastfeeding before taking NOLVADEX.
Tamoxifen is indicated to treat estrogen receptor positive metastatic breast cancer in adults, as an adjuvant in the treatment of early stage estrogen receptor positive breast cancer in adults, to reduce the risk of invasive breast cancer after surgery and radiation in adult women with ductal carcinoma in situ.
aprepitant.
artemether/lumefantrine.
black cohosh.
butalbital.
divalproex sodium.
eucalyptus.
fluconazole.
lapatinib.
Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Keep NOLVADEX out of reach of children
Do not store above 25°C
Consult a doctor before taking any medicines.
If you or anyone else accidentally takes too much of NOLVADEX, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are uncontrollable shaking of a part of the body, unsteadiness and dizziness.
Consult a doctor before taking any medicines.
Take NOLVADEX as advised by your physician. Swallow the medicine with water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
What is NOLVADEX used for?
It is used to treat breast cancer. This medicine is also used to treat infertility in women caused by a failure to produce and release eggs and reduce the risk of developing breast cancer.
What if I stop taking NOLVADEX?
Do not stop taking NOLVADEX, even if you start feeling well, unless your doctor tells you. Stopping it early may increase the risk of breast cancer coming back.
Can NOLVADEX be used in pregnant women?
No, NOLVADEX is not recommended for use in pregnant women as it can affect the unborn child.
