Manufacturer: Hetero Drugs Ltd
Salt Composition : Cefixime(50mg), Ofloxacin(50mg)
Bottle of 30ml Dry Syrup
(Inclusive of all taxes)
Give Office 50mg/50mg Dry Syrup to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. The dose and duration depend upon the type and severity of the infection, your child’s age, and body weight, so stick to the dose, time, and way prescribed by the doctor. If your child vomits within 30 minutes of intake, repeat the same dose but do not double dose if it's time for the next dose.
Do not give this medicine to your child in case of cold and flu symptoms. Such symptoms are almost always a result of viral infections, and antibiotics are ineffective in killing viruses. Antibiotics are given in cough and flu symptoms only when the doctor detects any underlying secondary bacterial infection.
This medicine may have some minor and temporary side effects such as vomiting, diarrhea, nausea, abdominal pain, and allergy. These side effects will disappear once your child’s body adapts to the medicine. However, if they persist or become bothersome for your child, report to the doctor without any delay.
Share your child’s complete medical history with your child’s doctor. Make sure the doctor knows if your child has or had any previous episode of allergy, heart problem, a blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.
Office 50mg/50mg Dry Syrup contains two antibiotics. Cefixime works by preventing the formation of the bacterial protective covering (cell wall) while ofloxacin directly interacts with the genetic material of bacteria. As a consequence, the infection-causing bacteria stop growing further and the spread of the infection is successfully arrested.
Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. Ofloxacin is mainly eliminated by renal excretion, where between 65% and 80% of an administered oral dose of ofloxacin is excreted unchanged via urine within 48 hours of dosing. About 4-8% of an ofloxacin dose is excreted in the feces and the drug is minimally subject to biliary excretion.
Office 50mg/50mg Dry Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Office
Loss of appetite
Allergy
Severe side effects of Office
Insomnia (difficulty in sleeping)
Dizziness
Headache
Hypersensitivity
Hypereosinophilia
Agranulocytosis (deficiency of granulocytes in the blood)
Decreased white blood cell count (lymphocytes)
Decreased white blood cell count (neutrophils)
Granulocytopenia
Hemolytic anemia
Low blood platelets
Thrombocytosis
Gastrointestinal disturbance
Increased liver enzymes
Increased bilirubin in the blood
Increased blood urea
Pseudomembranous colitis
Jaundice
Acute renal failure
Breathlessness
Seizure
Inflammation of tendons
Tendon rupture
Serum sickness
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome
Itching
Rash
Drug fever
Joint pain
Erythema multiforme
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Paresthesia (tingling or pricking sensation)
Psychotic disorder
If you are allergic to cefixime or ofloxacin.
If you are allergic to cephalosporins or similar medicines.
If you are a pregnant woman or a breastfeeding mother.
If you have a history of fits or any other brain-related disorders.
If you have a family history of red blood cell disorder.
Your child’s age and body weight. So stick to the dose, time, and way prescribed by the doctor.
Cefixime+Ofloxacin is used in adults for the treatment of typhoid fever and urinary tract infections.
CEFIXIME+OFLOXACIN should be avoided to be taken with vaccines including typhoid vaccine, cholera vaccine, and Bacillus Calmette Guerin (BCG vaccine), antiepileptic (carbamazepine), blood thinner (warfarin), antacid and ulcer treating medicine (aluminium hydroxide, magnesium hydroxide, cimetidine, sucralfate), medicine to treat excess uric acid (probenecid), medicines for arthritis (methotrexate), diuretics/water pills (furosemide), asthma medicine (theophylline) and pain killers (fenbufen, ibuprofen).
Check the label for directions before use. Dissolve the powder in sterile water. Shake well and use. Office 50mg/50mg Dry Syrup is to be taken with food.
Store below 30°C
Unless your child’s doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next dose. Do not give the double dose to catch up and follow the prescribed dosing schedule.
Consult a doctor before taking any medicines.
Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
Give this medicine with food to avoid an upset stomach.
Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
Do not give any calcium, magnesium, iron, vitamin, or antacid within 2 hours of taking Office 50mg/50mg Dry Syrup as these can affect the absorption of the medicine.
Conditions like common cold and flu are caused by viruses. Never use this medicine for such conditions.
Only give Office 50mg/50mg Dry Syrup to your child for their current infection. Never save medicine for future illnesses.
Stop this medicine and immediately report to your child’s doctor in case your child develops an itchy rash, facial swelling, or breathing difficulties while taking this medicine.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Dissolve the powder in sterile water. Shake well and use. Office 50mg/50mg Dry Syrup is to be taken with food.
Q. What if I give too much of Office 50mg/50mg Dry Syrup by mistake?
An extra dose of Office 50mg/50mg Dry Syrup is unlikely to do harm. However, you must still be vigilant because overdoses may cause unwanted side effects and may even worsen your child’s condition. If you think you have given too much of Office 50mg/50mg Dry Syrup to your child, speak to a doctor immediately.
Q. Are there any possible serious side effects of Office 50mg/50mg Dry Syrup?
Some serious side effects of this medicine include persistent vomiting, kidney damage, allergy, diarrhea, and severe gastrointestinal infections. Always consult your child’s doctor for help in such a situation.
Q. Can other medicines be given at the same time as Office 50mg/50mg Dry Syrup?
Office 50mg/50mg Dry Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Office 50mg/50mg Dry Syrup. Also, check with your child’s doctor before giving any medicine to your child.
Q. Can I get my child vaccinated while on treatment with Office 50mg/50mg Dry Syrup?
Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.
