Manufacturer: Abbott
Salt Composition : Ampicillin(500mg)
Olin 500mg Injection is a penicillin-type antibiotic used to treat a variety of bacterial infections of the skin, bones and joints, respiratory tract (e.g. pneumonia), urinary tract, gastrointestinal tract, brain (e.g, meningitis), heart, blood, and others.
Olin 500mg Injection is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. This medicine should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication. It is effective in both adults and children.
Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. Rash, vomiting, allergic reactions, nausea, diarrhea, and local pain, swelling, or redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.
The mechanisms of action of ampicillin are interference with cell wall synthesis by attachment to penicillin-binding proteins (PBPs), inhibition of cell wall peptidoglycan synthesis and inactivation of inhibitors to autolytic enzymes
Pharmacokinetics. Ampicillin is well-absorbed from the GI tract (though food reduces its absorption), and reaches peak concentrations in one to two hours. The bioavailability is around 62% for parenteral routes. Unlike other penicillins, which usually bind 60–90% to plasma proteins, ampicillin binds to only 15–20%.
Rash
Allergic reaction
Nausea
Diarrhea
Injection site reactions (pain, swelling, redness)
Vomiting
Contraindications. Ampicillin is contraindicated in those with a hypersensitivity to penicillins, as they can cause fatal anaphylactic reactions. Hypersensitivity reactions can include frequent skin rashes and hives, exfoliative dermatitis, erythema multiforme, and a temporary decrease in both red and white blood cells
Olin 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Olin 500mg Injection does not cause any harmful side effects.
Olin 500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Infections of the Genitourinary Tract Including gonorrhoea.
Infections of the Respiratory Tract.
Infections of the Gastrointestinal Tract.
Bacterial meningitis/septicaemia.
Endocarditis treatment.
Endocarditis prophylaxis (off-label)
Soft tissue infections.
allopurinol.
atenolol.
azithromycin.
bendroflumethiazide.
chloramphenicol.
chlorothiazide.
clarithromycin.
colestipol
Your doctor or nurse will give you this medicine.
Store below 30°C
If you miss a dose of Olin 500mg Injection, consult your doctor.
Consult a doctor before taking any medicines
Olin 500mg Injection is used to treat infections caused by bacteria.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Olin 500mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking this medicine and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can Olin 500mg Injection cause allergic reaction?
Although it is rare but yes, Olin 500mg Injection can cause allergic reaction and is harmful in patients with known allergy to penicillins. Get emergency medical help if you have any of the signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Q. How long does Olin 500mg Injection takes to work?
Usually, Olin 500mg Injection starts working soon after taking it. However, it may take around 2-3 days to make you feel better while taking Olin 500mg Injection.
Q. Can the use of Olin 500mg Injection cause diarrhea?
Yes, the use of Olin 500mg Injection can cause diarrhea. It is an antibiotic and it kills the harmful bacteria, however, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If diarrhea persists, talk to your doctor about it.
