Manufacturer: Alkem Laboratories Ltd
Salt Composition : Olmesartan Medoxomil(40mg), Amlodipine(5mg)
Olkem 40 AM Tablet may be taken on an empty stomach or along with food. However, it is better to take it regularly at a fixed time each day, as prescribed by your doctor. The dose will depend on your condition and how you respond to the medicine. It is important to keep taking this medicine even if you feel well. By lowering your blood pressure, it is reducing your risk of heart attack or stroke so do not stop taking it unless your doctor tells you to. You can help this medication work better by making a few changes to your lifestyle by being active, stopping smoking and eating low salt and low-fat diet.
The most common side effects of this medicine include swelling in your ankles or feet (edema), sleepiness, dizziness, headache, taste change, upset stomach, and tiredness. Since it may cause sleepiness and dizziness, do not drive or do anything requiring concentration until you know how it affects you. Talk to your doctor if any of the side effects bother you or do not go away.
Before taking this medicine, let your doctor know if you have any kidney or liver problems or severe dehydration. Pregnant or breastfeeding women should also consult their doctor before taking it. While using this medicine, your blood pressure will be monitored regularly and your kidney function may also need to be tested.
Olmesartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes the blood vessels to tighten. As a result, olmesartan relaxes blood vessels. This lowers the blood pressure and increases the supply of blood and oxygen to the heart.
during absorption, there is virtually no further metabolism of olmesartan. Total plasma clearance of olmesartan is 1.3 L/h, with a renal clearance of 0.6 L/h. Approximately 35% to 50% of the absorbed dose is recovered in urine while the remainder is eliminated in feces via the bile.
Pharmacokinetics and Metabolism: After oral administration of therapeutic doses of amlodipine besylate tablets, absorption produces peak plasma concentrations between 6 and 12 hours. Absolute bioavailability has been estimated to be between 64 and 90%.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Olkem AM
Sleepiness
Taste change
Ankle swelling
Headache
Flushing (sense of warmth in the face, ears, neck and trunk)
Dizziness
Tiredness
Palpitations
Upset stomach
Increased potassium level in blood
If you have diabetes, do not use amlodipine and olmesartan together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking amlodipine and olmesartan with aliskiren if you have kidney disease.
Olkem 40 AM Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Olkem 40 AM Tablet.
Olkem 40 AM Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Amlodipine and olmesartan is a combination of medicines that may be used alone or with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
If you have diabetes, do not use amlodipine and olmesartan together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking amlodipine and olmesartan with aliskiren if you have kidney disease.
Do not chew, crush or break it. Olkem 40 AM Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Olkem 40 AM Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Olkem 40 AM Tablet is a combination of two medicines that provides better blood pressure control than either medicine alone.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
It may cause you to feel lightheaded or weak especially when you stand up. Rise slowly if you have been sitting or lying down.
Avoid consuming alcohol as it may enhance the blood pressure lowering effect of Olkem 40 AM Tablet.
It can cause ankle or foot swelling. Raise your legs while you are sitting down and talk to your doctor if it does not go away.
Do not take Olkem 40 AM Tablet Tablet if you are pregnant, planning to conceive or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olkem 40 AM Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How long does it take for Olkem 40 AM Tablet to work?
You may notice a decrease in your blood pressure effectively within 2 weeks of starting Olkem 40 AM Tablet. However, it may take about 8 weeks to see the full benefits of this medicine. Talk to your doctor in case you have any concerns regarding Olkem 40 AM Tablet, but do not stop taking it without consulting the doctor.
Q. At what time of the day should you take Olkem 40 AM Tablet?
Your doctor may suggest to take your first dose before bedtime, considering that this medicine can make you feel dizzy. After the very first dose you can take Olkem 40 AM Tablet at any time of the day. It is important to take this medicine at the same time every day.
Q. Can I feel dizzy after taking Olkem 40 AM Tablet?
Yes, the use of Olkem 40 AM Tablet can make you feel dizzy. This may occur when you suddenly get up from a lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Q. What are the other lifestyle changes I should make while using Olkem 40 AM Tablet?
Lifestyle changes play a major role in keeping you healthy if you are taking Olkem 40 AM Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Olkem 40 AM Tablet and to keep yourself healthy.