Manufacturer: Khandelwal Laboratories Pvt Ltd
Salt Composition : Cyclophosphamide(200mg)
Vial of 1 Injection
(Inclusive of all taxes)
Oncomide 200mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Cyclophosphamide is an alkylating agent of the nitrogen mustard type. 2 An activated form of cyclophosphamide, phosphoramide mustard, alkylates, or binds, to DNA. Its cytotoxic effect is mainly due to cross-linking of strands of DNA and RNA, and to inhibition of protein synthesis
Cyclophosphamide is inactive until it undergoes hepatic transformation to form 4-hydroxycyclophosphamide, which then breaks down to form the ultimate alkylating agent, phosphoramide mustard.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oncomide
Vomiting
Nausea
Hair loss
Fever
Blood in urine
Diarrhea
Decreased white blood cell count (neutrophils)
a bacterial infection.
chickenpox.
shingles.
opportunistic fungal infection.
an infection due to a protozoa organism.
an infection due to a parasite.
myeloproliferative neoplasm.
low amount of sodium in the blood
Oncomide 200mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Oncomide 200mg Injection.
Oncomide 200mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Cyclophosphamide is indicated for the treatment of biopsy proven minimal change nephrotic syndrome in pediatrics patients who failed to adequately respond to or are unable to tolerate adrenocorticosteroid therapy
adenovirus types 4 and 7 live, oral.
carbamazepine.
etanercept.
hydrochlorothiazide.
idarubicin.
idelalisib.
influenza virus vaccine trivalent, adjuvanted.
ivacaftor.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Oncomide 200mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Oncomide 200mg Injection helps in the treatment of cancer.
It is injected into the vein by a doctor or healthcare professional.
Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
Do not take Oncomide 200mg Injection if you are pregnant or breastfeeding.
Use effective contraception method to prevent pregnancy while taking this medicine.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can Oncomide 200mg Injection cause infertility?
Yes, Oncomide 200mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Oncomide 200mg Injection.
Q. Do I need to avoid sun exposure during treatment with Oncomide 200mg Injection?
No, there is no evidence that you need to avoid sun exposure while on Oncomide 200mg Injection. Skin and nail discoloration are reported rarely with Oncomide 200mg Injection.
Q. Can Oncomide 200mg Injection cause cancer?
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Oncomide 200mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Oncomide 200mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Q. Is Oncomide 200mg Injection chemotherapy medicine?
Yes, Oncomide 200mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Q. Can Oncomide 200mg Injection be used for non-cancer condition?
Yes, Oncomide 200mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Oncomide 200mg Injection for nephrotic syndrome has not been established.
Q. Can Oncomide 200mg Injection causes weight loss?
Yes, Oncomide 200mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.
