Manufacturer: Lupin Ltd
Salt Composition : Metformin(1000mg), Linagliptin(2.5mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Ondero Met 2.5mg/1000mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking this medicine with meals helps to reduce the chances of developing an upset stomach.
You should take it regularly, at the same time each day, to get the most benefit. You should not stop this medicine unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.
The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, blocked nose (nasal congestion), and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin, glimepiride, or sulphonylurea. So you need to know how to recognize and deal with it.
Ondero Met 2.5mg/1000mg Tablet is a combination of two antidiabetic medicines: Metformin and Linagliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's sensitivity to insulin. Linagliptin is a DPP-4 inhibitor which works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.
Metformin is rapidly distributed following absorption and does not bind to plasma proteins. No metabolites or conjugates of metformin have been identified. The absence of liver metabolism clearly differentiates the pharmacokinetics of metformin from that of other biguanides, such as phenformin.The pharmacokinetics of linagliptin has been extensively characterised in healthy subjects and patients with type 2 diabetes. After oral administration of a 5 mg dose to healthy volunteers or patients, linagliptin was rapidly absorbed, with peak plasma concentrations (median Tmax) occurring 1.5 hours post-dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ondero Met
Hypoglycemia (low blood glucose level)
Nausea
Diarrhea
Vomiting
Flatulence
Weight gain
If you are suffering from any of the following diseases, you should not take Metformin + Linagliptin unless your doctor advises you to do so -
Pancreatitis
Vitamin B12 Deficiency
Ondero Met 2.5mg/1000mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Ondero Met 2.5mg/1000mg Tablet.
Ondero Met 2.5mg/1000mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
Linagliptin and metformin combination is used to treat high blood sugar levels caused by type 2 diabetes. Linagliptin helps to control blood sugar levels by increasing substances in the body that make the pancreas release more insulin.
LINAGLIPTIN+METFORMIN interacts with anti-depressants (bupropion), pain killers (aspirin), antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (ranolazine, digoxin), anti-HIV drugs (dolutegravir), anti-hypertensives (amlodipine, verapamil), anti-epileptic drugs (topiramate, lamotrigine), oral contraceptives.
Do not chew, crush or break it. Ondero Met 2.5mg/1000mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Ondero Met 2.5mg/1000mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
Ondero Met 2.5mg/1000mg Tablet should be taken with food to lower the chances of having an upset stomach.
Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, or stomach pain as Ondero Met 2.5mg/1000mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ondero Met 2.5mg/1000mg Tablet is to be taken with food.
Q. Can the use of Ondero Met 2.5mg/1000mg Tablet cause lactic acidosis?
Yes, the use of Ondero Met 2.5mg/1000mg Tablet can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Ondero Met 2.5mg/1000mg Tablet and immediately consult your doctor.
Q. What are the possible side effects of Ondero Met 2.5mg/1000mg Tablet?
The use of Ondero Met 2.5mg/1000mg Tablet may cause some common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. It can also lead to a serious but rare side effect known as lactic acidosis. Additionally, its long-term use can also lead to vitamin B12 deficiency.
Q. Are there any specific conditions in which Ondero Met 2.5mg/1000mg Tablet should not be taken?
The use of Ondero Met 2.5mg/1000mg Tablet should be avoided in patients with known allergy to any of the components of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis. Therefore, consult your doctor before using Ondero Met 2.5mg/1000mg Tablet.
Q. Is it safe to take alcohol while I am also taking Ondero Met 2.5mg/1000mg Tablet?
No, it is not safe to take Ondero Met 2.5mg/1000mg Tablet along with alcohol. Doing so can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or kidney dysfunction. However, if you are not sure, consult your doctor.
Q. What are the instructions for the storage and disposal of Ondero Met 2.5mg/1000mg Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can the use of Ondero Met 2.5mg/1000mg Tablet cause hypoglycemia?
The use of Ondero Met 2.5mg/1000mg Tablet does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.
Q. Can the use of Ondero Met 2.5mg/1000mg Tablet lead to vitamin B12 deficiency?
Yes, long-term use of Ondero Met 2.5mg/1000mg Tablet can cause vitamin B12 deficiency as it interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.
