Manufacturer: AstraZeneca
Salt Composition : Saxagliptin(2.5mg)
Onglyza 2.5mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or in combination with other diabetes medicines. It can be taken with or without food.
The dose will depend on your condition and blood sugar levels. Use it strictly as advised by your doctor. Do not stop taking the medicine unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of this medicine include hypoglycemia, upper respiratory tract infection, urinary tract infection, headache, and peripheral edema. It is important to recognize the symptoms of hypoglycemia (such as lightheadedness, sweating, dizziness, fainting, and dry mouth) and know how to deal with it. You can carry sugar or glucose candy and have them to control your symptoms if you experience any. Contact your doctor if any of these side effects do not go away or worry you.
Onglyza 2.5mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.
Saxagliptin is metabolized by cytochrome P450 (CYP) 3A4/5 and is eliminated by a combination of renal and hepatic clearance.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Onglyza
Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
Upper respiratory tract infection
Urinary tract infection
Headache
Peripheral edema
Taking insulin or other anti-diabetic medication
AIDS
Acute liver disease
Pancreatic disease
Any other medications taken recently or treated for fits, chronic pain, any infection, or high blood pressure
Kidney disease or heart failure
Type 1 diabetes
Diabetes complications
Hypersensitivity
Onglyza 2.5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Onglyza 2.5mg Tablet.
Onglyza 2.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Saxagliptin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings
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Do not chew, crush or break it. Onglyza 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Onglyza 2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Onglyza 2.5mg Tablet should be taken at the same time every day since this helps you remember to take it.
Be careful while driving or operating machinery until you know how Onglyza 2.5mg Tablet affects you.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Onglyza 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Does Onglyza 2.5mg Tablet cause any weight loss (reduction)?
No, Onglyza 2.5mg Tablet neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Onglyza 2.5mg Tablet is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.
Q. What is the benefit of using Onglyza 2.5mg Tablet with insulin?
Onglyza 2.5mg Tablet when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.
Q. Are there any contraindications to the use of Onglyza 2.5mg Tablet?
Yes, the use of Onglyza 2.5mg Tablet is contraindicated in some conditions like a history of allergy to Onglyza 2.5mg Tablet, any ingredients of this drug or to any other drug of the same class. Onglyza 2.5mg Tablet should also be avoided in patients with a history of pancreatitis.
Q. Is it beneficial to use Onglyza 2.5mg Tablet with glipizide?
Yes, it is beneficial to take Onglyza 2.5mg Tablet and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better controlling of blood sugar levels.
Q. Can Onglyza 2.5mg Tablet be used with other diabetes medicines?
Yes, Onglyza 2.5mg Tablet can be used alone or in combination with other diabetes medicines, along with proper diet and exercise.
Q. Can the use of Onglyza 2.5mg Tablet cause hypoglycemia (low blood sugar)?
Usually, Onglyza 2.5mg Tablet does not cause hypoglycemia when used alone in diabetes. However, it may cause low blood sugar when combined with other medicines like insulin and sulfonylureas.
