Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Calcitonin(Salmon)(200IU)
Ostospray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat for the other nostril. You should take adequate supplements of calcium and vitamin D while on the treatment of this medicine to make it more effective.
The most common side effects of this medicine include runny nose, nose bleed, back pain, joint pain, headache, and other nose symptoms such as itching, irritation, and discomfort. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
Ostospray is a calcitonin receptor agonist. It acts by suppressing the activity of osteoclasts, cells that cause destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.
When used as a nasal spray, calcitonin takes around 13 to 15 minutes to be absorbed into the blood. The half-life of commercially prepared calcitonin is around 18 to 20 minutes.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ostospray
Runny nose
Nosebleeds
Nasal irritation
Back pain
Joint pain
Headache
Calcitonin is contraindicated in individuals with known hypersensitivity or allergic reactions to the drug or its components. Hypersensitivity reactions can manifest as mild skin responses or escalate to severe anaphylaxis. The FDA has not issued any specific Box Warnings for calcitonin.
Ostospray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Ostospray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Currently, the U.S. Food and Drug Administration approved calcitonin for the management of postmenopausal osteoporosis, Paget's disease of bone, and hypercalcemia. The drug's clinical significance derives from its ability to inhibit osteoclast activity and increase the renal excretion of calcium.
Drug-Drug interactions: CALCITONIN may interact with certain medicines used to treat mood disorders (e.g. lithium), medicines used to treat secondary hyperparathyroidism (e.g. etelcalcetide) and antiviral medications (e.g. foscarnet).
Drug-Food interactions: No interaction found.
Drug-Disease interactions: CALCITONIN interacts with disease conditions, including hypocalcaemia (low calcium level) and mineral metabolism disorder.
Drug-Drug Interactions Checker List:
LITHIUM
ETELCALCETIDE
FOSCARNET
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Ostospray, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Ostospray to make your bones stronger, and lower the risk of fractures.
It is used in women with osteoporosis who have undergone menopause.
It may cause temporary dizziness. Don't drive or do anything requiring concentration until you know how it affects you.
Unopened bottles should be stored in the refrigerator. Once opened, they should be stored at room temperature for up to 35 days.
Stop using it and inform your doctor if you get any nosebleeds or notice any ulceration inside your nose.
Discontinue Ostospray and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Use it as advised by your doctor or check the label for directions before use.
Q. Does Ostospray need to be refrigerated?
Yes, an unopened bottle of Ostospray need to be refrigerated. It should be kept at a temperature between 2°C and 8°C. Do not freeze. After opening the bottle of Ostospray, store it at room temperature between 15°C and 30°C.
Q. Does Ostospray increase bone density?
Ostospray contains calcitonin which is a hormone that is naturally produced by the thyroid gland and is responsible for maintaining calcium balance in the body. Ostospray decreases the bone loss and damage in patients with osteoporosis. In some cases, it also helps in bone formation by activating the bone forming cells, thereby increasing the bone density.
Q. Can Ostospray reduce the calcium levels in blood?
Yes, Ostospray can reduce the levels of calcium in the blood. If the calcium levels in your blood drop down severely then it can present with numbness or tingling in your fingers, toes, or around your mouth. The blood calcium levels need to be monitored in such cases. Immediately contact your doctor if you experience any such symptoms.
Q. How should I use Ostospray?
Follow the directions given by your prescriber and do ask him in case of any doubts. Usually, it is to be given in single nostril once daily. To start with we take 1 spray in left nostril on day 1, followed by right nostril on the second day. Continue to take the medicine inside the nose by switching nostrils every alternate day. Each bottle is set to deliver 30 doses. Do not use the bottle after 30 days.
