Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Oxaliplatin(100mg)
Oxa 100mg Infusion is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.
Oxa 100mg Infusion is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
After a single 2-hour intravenous infusion of oxaliplatin at a dose of 85 mg/m2, pharmacokinetic parameters expressed as ultrafiltrable platinum was Cmax of 0.814 mcg/mL. Interpatient and intrapatient variability in ultrafiltrable platinum exposure (AUC0-48hr) assessed over 3 cycles was 23% and 6%, respectively.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oxa
Nausea
Fatigue
Anemia (low number of red blood cells)
Vomiting
Diarrhea
Decreased white blood cell count (neutrophils)
Low blood platelets
Increased liver enzymes
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)
Platinum hypersensitivity anaphylaxis[30]
Posterior reversible encephalopathy syndrome[33]
Grade 3 or 4 peripheral sensory neuropathy[34]
Severe renal impairment[35]
Chronic lung disease[36]
Rhabdomyolysis[37]
Sepsis[38]
Pregnant or intending to get pregnant[39]
Oxa 100mg Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Oxa 100mg Infusion. Please consult your doctor.
Oxa 100mg Infusion is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Oxaliplatin, in combination with infusional fluorouracil and leucovorin, is indicated for the treatment of advanced colorectal cancer and adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor.
Drug-Drug Interactions: Inform the doctor if you are taking medicines that prolong QT interval (antiarrhythmic agents), nephrotoxic products, or anti-coagulants.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform the doctor if you have an infection, lung, liver or kidney problems, bleeding problems, heart problems (long QT syndrome, irregular/slow heartbeat), or changes in electrolyte levels.
Kindly do not self-administer.
Store below 30°C
If you miss a dose of Oxa 100mg Infusion, please consult your doctor.
Consult a doctor before taking any medicines.
Oxa 100mg Infusion is given as an injection into veins under the supervision of a doctor.
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
