Manufacturer: Lupin Ltd
Salt Composition : Levosulpiride(75mg), Pantoprazole(40mg)
Strip of 10 Capsule
(Inclusive of all taxes)
P2I L 75mg/40mg Capsule is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are stomach pain, vomiting, diarrhea, headache, nausea, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food, or chocolate can help you to get better results.
P2I L 75mg/40mg Capsule is a combination of two medicines: Levosulpiride and Pantoprazole. Levosulpiride is a prokinetic which works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of stomach and intestines, and prevents reflux (acid going up to the food pipe). Pantoprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and ulcers.
The main mechanism of action of levosulpiride consists of blocking the D2 dopaminergic receptors, preferentially located on the presynaptic membranes in the dopaminergic pathways of the brain; this means that sulpiride is a selective autoreceptor blocker.Pantoprazole shows linear pharmacokinetics after both i.v. and oral administration. Pantoprazole is extensively metabolized in the liver, has a total serum clearance of 0.1 l/h/kg, a serum elimination halflife of about 1.1 h, and an apparent volume of distribution of 0.15 l/kg.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of P2I L
Stomach pain
Vomiting
Diarrhea
Headache
Nausea
Flatulence
Dizziness
If you are suffering from any of the following diseases, you should not take Levosulpiride + Pantoprazole unless your doctor advises you to do so -
Mania
Gastrointestinal Bleeding
Heart Disease
Asthma
Gastric Cancer
Diarrhea (Loose Motions)
Osteoporosis
Liver Disease
P2I L 75mg/40mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
P2I L 75mg/40mg Capsule may cause excessive drowsiness with alcohol.
P2I L 75mg/40mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
Gastroesophageal Reflux Disease
Mental Disorder
Depression
Frequent Persistent Heartburn
Irritable Bowel Syndrome
Indigestion
Heartburn
Back Flow Of Acid From Stomach
Difficulty In Swallowing
Inflammation Of Esophagus
Excess Acid Secretion By Stomach
Intestinal Or Stomach Ulcers
LEVOSULPIRIDE+PANTOPRAZOLE may interact with medicines such as anti-fungal (ketoconazole, itraconazole, posaconazole) anti-cancer (erlotinib), blood thinner (warfarin, phenprocoumon), anti-HIV (atazanavir), a drug used to treat rheumatoid arthritis, psoriasis, and cancer (methotrexate), anti-depressant (fluvoxamine), antibiotic (rifampicin), and herbal supplement (St John’s wort).
P2I L 75mg/40mg Capsule is to be taken empty stomach.
Store below 30°C
If you miss a dose of P2I L 75mg/40mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
P2I L 75mg/40mg Capsule is prescribed to give relief from acidity and its associated symptoms.
It is a well-tolerated medicine and provides relief for a long time.
Take it one hour before the meal, preferably in the morning.
Inform your doctor if you get watery diarrhea or stomach pain that does not go away.
Do not consume alcohol while taking P2I L 75mg/40mg Capsule as it can increase the risk of stomach damage.
Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take P2I L 75mg/40mg Capsule for longer than prescribed.
P2I L 75mg/40mg Capsule is prescribed to give relief from acidity and its associated symptoms.
Take this medicine in the dose and duration as advised by your doctor. P2I L 75mg/40mg Capsule is to be taken empty stomach.
Q. What is the best time to take P2I L 75mg/40mg Capsule?
Take P2I L 75mg/40mg Capsule exactly as directed by your doctor. It is best to take one capsule on an empty stomach daily.
Q. What are the contraindications associated with the use of P2I L 75mg/40mg Capsule?
The use of P2I L 75mg/40mg Capsule should be avoided in patients with known allergy to any of the components or excipients of this medicine.
Q. Can the use of P2I L 75mg/40mg Capsule cause dizziness?
Yes, the use of P2I L 75mg/40mg Capsule can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
Q. Does the use of P2I L 75mg/40mg Capsule lead to increased risk of fractures?
Several studies in adults suggest that P2I L 75mg/40mg Capsule may increase the risk of osteoporosis-related fractures of the hip, wrist or spine. The risk of fracture was more in patients who received high dose. High dose can mean multiple daily doses, and long-term therapy (a year or longer).
