Pari 37.5mg Tablet CR (15'S)

Manufacturer: Ipca Laboratories Ltd

Salt Composition : Paroxetine(37.5mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Pari CR 37.5 Tablet helps many people to recover from depression by improving their mood and relieving anxiety and tension. It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.

Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).

To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Some common side effects of Pari CR 37.5 Tablet include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.


Basic Information

Mechanism Of Action

As an SSRI class drug, paroxetine's signature mechanism of action is to block the serotonin reuptake transporter (SERT) and thus increase the concentration of synaptic serotonin.

Pharmacokinets

Pharmacokinetics: Paroxetine hydrochloride is completely absorbed after oral dosing of a solution of the hydrochloride salt. The mean elimination half-life is approximately 21 hours (CV 32%) after oral dosing of 30 mg tablets of PAXIL daily for 30 days.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pari

Nausea

Fatigue

Dryness in mouth

Loss of appetite

Increased sweating

Dizziness

Nervousness

Tremors

Low sexual desire

Insomnia (difficulty in sleeping)

Confusion

Constipation

Erectile dysfunction

Delayed ejaculation

Decreased libido


Contra Indications

a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone.

low amount of sodium in the blood.

an increased risk of bleeding.

manic behavior.

manic-depression.

suicidal thoughts.

serotonin syndrome, a type of disorder with high serotonin levels.


Pregnancy Related Information

Pari CR 37.5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Pari CR 37.5 Tablet.


Breast Feeding Related Information

Pari CR 37.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Indications

Paroxetine tablets, suspension (liquid), and extended-release (long-acting) tablets are used to treat depression, panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks), and social anxiety disorder (extreme fear of interacting with others or performing

Interactions

Do not use paroxetine with buspirone (Buspar), fentanyl (Abstral, Duragesic), lithium (Eskalith, Lithobid), tryptophan, St. John's wort, amphetamines, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova, Imitrex, Maxalt, Relpax, Ultram, Zomig).

Typical Dosage

Pari CR 37.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Pari CR 37.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

It can take 2-3 weeks for Pari CR 37.5 Tablet to start working.

Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.

If your doctor asks you to stop Pari CR 37.5 Tablet, you should reduce the dose slowly over 4 weeks.

Avoid consuming alcohol when taking Pari CR 37.5 Tablet, as it may cause excessive drowsiness and calmness.

The addiction/dependence potential of Pari CR 37.5 Tablet is very less.


How To Use

Use it as advised by your doctor or check the label for directions before use. Pari CR 37.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

FAQs

Q. After how many days of taking Pari CR 37.5 Tablet will I start feeling better?

You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.

Q. I feel that my symptoms have worsened after having started taking Pari CR 37.5 Tablet. Can I stop it on my own or do I need to consult the doctor?

No, do not stop taking Pari CR 37.5 Tablet abruptly, without consulting your doctor. This is a common problem with Pari CR 37.5 Tablet that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.

Q. Can Pari CR 37.5 Tablet affect my sex life?

Yes, Pari CR 37.5 Tablet use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.

Q. What is the effect of Pari CR 37.5 Tablet on children?

Pari CR 37.5 Tablet should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Pari CR 37.5 Tablet. If your doctor has prescribed Pari CR 37.5 Tablet for your child and you are worried about these side effects, discuss it with your doctor.