Manufacturer: Ipca Laboratories Ltd
Salt Composition : Methylcobalamin(1500mcg), Pregabalin(75mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Pegsr M 1500 mcg/75 mg Tablet is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.
Some common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron). You should take this medicine as prescribed by your doctor.
Pharmacokinetics. Methylcobalamin can be administered orally, parenterally and intranasal. Methylcobalamin binds with an intrinsic factor and form a complex which is absorbed in distal ileum. Its half life is 6 days.
Pregabalin subtly reduces the synaptic release of several neurotransmitters, apparently by binding to alpha2-delta subunits, and possibly accounting for its actions in vivo to reduce neuronal excitability and seizures.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pegsr M
Dizziness
Sleepiness
Tiredness
Uncoordinated body movements
METHYLCOBALAMIN+PREGABALIN should be used with caution in patients with liver diseases, kidney diseases, heart problems, alcoholism, drug abuse, and suicidal tendencies.
Pegsr M 1500 mcg/75 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Pegsr M 1500 mcg/75 mg Tablet may cause excessive drowsiness with alcohol.
Pegsr M 1500 mcg/75 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Methylcobalamin+Pregabalin is a combination of two medicines: Pregabalin and Methylcobalamin. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation.
Drug-Drug Interaction: METHYLCOBALAMIN+PREGABALIN may interact with a pain killer (oxycodone), opioids, antianxiety drugs (lorazepam), antacid (omeprazole), antibiotic (neomycin), and anti-gout medication (colchicine). Drug-Food Interaction: Avoid alcohol consumption while using METHYLCOBALAMIN+PREGABALIN.
Do not chew, crush or break it. Pegsr M 1500 mcg/75 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Pegsr M 1500 mcg/75 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Pegsr M 1500 mcg/75 mg Tablet for treating and preventing nerve pain.
Its side effects are usually mild and temporary.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid consuming alcohol when taking Pegsr M 1500 mcg/75 mg Tablet, as it may cause excessive sleepiness.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pegsr M 1500 mcg/75 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Pegsr M 1500 mcg/75 mg Tablet?
Pegsr M 1500 mcg/75 mg Tablet is a combination of two medicines: Pregabalin and Methylcobalamin. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
Q. Can I stop taking Pegsr M 1500 mcg/75 mg Tablet when my pain is relieved?
No, you should not stop taking Pegsr M 1500 mcg/75 mg Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pegsr M 1500 mcg/75 mg Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Pegsr M 1500 mcg/75 mg Tablet before you stop the medication completely.
Q. How to manage weight gain associated with the use of Pegsr M 1500 mcg/75 mg Tablet?
Pegsr M 1500 mcg/75 mg Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Q. Can the use of Pegsr M 1500 mcg/75 mg Tablet cause sleepiness or drowsiness?
Yes, Pegsr M 1500 mcg/75 mg Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
