Pegvir 100mcg Injection (1ml)

Manufacturer: Cipla Ltd

Salt Composition : Pegylated Interferon Alpha 2B(100mcg)


Pegvir 100mcg Injection is given as an injection by a qualified medical professional. You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.


Some common side effects of this medicine include headache, dizziness,  insomnia, vomiting, and nausea. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you notice fever, chills, rash, trouble breathing, unusual bleeding or bruising, and dark-colored urine. Regular blood tests are required to check your blood cells along with thyroid function, liver function, kidney function, and serum electrolyte levels.


Before taking it, tell your doctor if have liver, or kidney problems or have mental illness. You must inform your doctor if you notice mood changes, depression, vision changes, and suicidal thoughts while taking this medicine. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Basic Information

Mechanism Of Action

Pegvir 100mcg Injection modulates the body's immune system.

Pharmacokinets

Peginterferon alfa-2b reaches peak plasma concentration 15-44 hours after subcutaneous administration Label. The mean absorption half-life is 4.6 hours.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pegvir

Abdominal pain

Agitation

Anxiety

Blurred vision

Cough

Decreased appetite

Decreased white blood cell count

Depression

Dizziness

Dryness in mouth

Fatigue

Headache

Impaired concentration

Indigestion

Insomnia (difficulty in sleeping)

Nausea

Nervousness

Sore throat

Stomatitis (Inflammation of the mouth)

Viral infection

Vomiting

Contra Indications

Peginterferon alfa-2b is contraindicated in conditions like Autoimmune hepatitis, Hypersensitivity to the drug.


Pregnancy Related Information

Pegvir 100mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Product And Alcohol Interaction

Caution is advised when consuming alcohol with Pegvir 100mcg Injection. Please consult your doctor.

Breast Feeding Related Information

Pegvir 100mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Indications

Indications. Peginterferon alfa-2b is indicated for the treatment of patients with chronic hepatitis C who have compensated liver disease.


Interactions

The risk or severity of adverse effects can be increased when Peginterferon alfa-2b is combined with Canakinumab. The metabolism of Candesartan cilexetil can be increased when combined with Peginterferon alfa-2b. The risk or severity of bleeding can be increased when Cangrelor is combined with Peginterferon alfa-2b.


Typical Dosage

Kindly do not self administer.

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.

Effects Of Missed Dosage

If you miss a dose of Pegvir 100mcg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Pegvir 100mcg Injection helps treat chronic hepatitis C in adults.

Do not drive or do anything that requires mental focus until you know how it affects you.

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and 4 months after stopping the treatment.

Your doctor may get regular blood tests done to monitor your blood cells, liver and thyroid function, and lipid levels during treatment with this medicine.

Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Inform your doctor if you notice any changes in your behavior, mood or vision.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.