Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Pemetrexed(500mg)
Pemecad 500mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.
Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Pemetrexed interacts with DNA (genetic material) and causes certain changes in the DNA. This results in problems in DNA synthesis leading to anti-cancer effects.
The pharmacokinetics of pemetrexed do not change over multiple treatment cycles. Pemetrexed has a steady-state volume of distribution of 16.1 liters. In vitro studies indicate that pemetrexed is approximately 81% bound to plasma proteins.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pemecad
Nausea
Vomiting
Sore throat
Loss of appetite
Stomatitis (Inflammation of the mouth)
Hair loss
Low blood platelets
Rash
Fatigue
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Neuropathy
Pemetrexed is contraindicated in patients with a history of severe hypersensitivity reaction to pemetrexed. A sometimes fatal, serious rash including bullous, blistering, and exfoliative skin toxicity and cases suggestive of Stevens-Johnson syndrome or toxic epidermal necrolysis can occur with pemetrexed.
Pemecad 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Pemecad 500mg Injection does not cause any harmful side effects.
Pemecad 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Pemetrexed is indicated for the maintenance treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer whose disease has not progressed after four cycles of platinum-based first-line chemotherapy.
There are 3 disease interactions with pemetrexed which include: myelosuppression. liver dysfunction. renal dysfunction.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Pemecad 500mg Injection, consult your doctor.
Consult a doctor before taking any medicines.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Pemecad 500mg Injection a vesicant?
No. Pemecad 500mg Injection is not a vesicant.
Q. Is Pemecad 500mg Injection safe?
Pemecad 500mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Does Pemecad 500mg Injection cause hair loss?
Yes. Pemecad 500mg Injection is a prescription chemotherapy medication and hair loss is one of the possible side effects.
