Manufacturer: Apostle Remedies
Salt Composition : Amoxycillin(125mg), Clavulanic Acid(125mg)
Vial of 1 Injection
(Inclusive of all taxes)
Penom Clav 125mg/125mg Injection is generally administered by a healthcare professional and should not be self-administered. Depending on the severity of your underlying illness, your doctor will decide the precise dose and schedule as per which this injection is to be given. It is strictly advised to be used as per the doctor’s prescription.
Common side effects of this medicine include nausea, vomiting, and diarrhea. Additionally, you may notice some injection site reactions like pain, swelling, or redness. Please consult your doctor if these do not get better or persist for a longer duration of time. In cases of patients with severe liver or kidney disease, consult your doctor before you start with the treatment.
Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Your doctor may change the dose or prescribe a different medicine. This medicine is generally regarded as safe to use during pregnancy and breastfeeding if used under a doctor’s supervision.
Penom Clav Injection acts by killing the bacteria responsible for the infections. However, bacteria make an enzyme (beta-lactamases) that can destroy amoxicillin. Clavulanic acid inactivates this enzyme and hence helps amoxicillin to function optimally.
Amoxicillin is approximately 60% bioavailable. A 250mg dose of oral amoxicillin reaches a Cmax 3.93±1.13mg/L with a Tmax 1.31±0.33h and an AUC of 27.29±4.72mg*h/L. A 875mg dose of oral amoxicillin reaches a Cmax 11.21±3.42mg/L with a Tmax 1.52±0.40h and an AUC of 55.04±12.68mg*h/L.Clavulanic acid is well absorbed after oral ingestion in adult men, with a mean bioavailability of 60%. Peak concentrations are reached on average 0.7–2.0 h after ingestion. Its metabolism is partly hepatic with plasma protein binding up to 30% and it is cleared through both renal and non-renal pathways.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Penom Clav
Vomiting
Nausea
Diarrhea
If you are suffering from any of the following diseases, you should not take Amoxicillin + Clavulanic Acid unless your doctor advises you to do so -
Diarrhea (Loose Motions)
Hepatitis
Kidney Disease
Jaundice
Hepatic Encephalopathy
Penom Clav 125mg/125mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Penom Clav 125mg/125mg Injection does not cause any harmful side effects.
Penom Clav 125mg/125mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
The combination of amoxicillin and clavulanic acid is used to treat certain infections caused by bacteria, including infections of the ears, lungs, sinus, skin, and urinary tract. Amoxicillin is in a class of medications called penicillin-like antibiotics. It works by stopping the growth of bacteria.
AMOXICILLIN+CLAVULANIC ACID may have interaction with anti-gout (allopurinol, probenecid), anticoagulants (warfarin), anti-cancer (methotrexate), and immunosuppressant (mycophenolate mofetil).
Kindly do not self administer.
Store below 30°C
If you miss a dose of Penom Clav 125mg/125mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Penom Clav 125mg/125mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Penom Clav 125mg/125mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is Penom Clav 125mg/125mg Injection?
Penom Clav 125mg/125mg Injection is a combination of two medicines: Amoxycillin and Clavulanic acid. It is used to treat bacterial infections like, tonsillitis, sinusitis, otitis media, respiratory tract infections, urinary tract infections, boils, abscesses, cellulitis, wound infection, bone infection, and oral cavity infections.. The medicine works by killing the harmful bacteria that cause infections.
Q. Is it safe to use Penom Clav 125mg/125mg Injection?
Penom Clav 125mg/125mg Injection is safe to use when taken as advised by the doctor. However, in some patients, it may cause common side effects like diarrhea, nausea, vomiting, rash, allergic reaction and other uncommon or rare side effects. If you experience any persistent problem during the course of your treatment, inform your doctor as soon as possible.
Q. How is Penom Clav 125mg/125mg Injection administered?
Penom Clav 125mg/125mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Penom Clav 125mg/125mg Injection.
Q. Are there any specific cautions associated with the use of Penom Clav 125mg/125mg Injection?
The use of Penom Clav 125mg/125mg Injection is considered to be harmful for patients with known allergy to penicillins or any other ingredient of the medicine. It should not be used in patients with a history of liver disease. Therefore, inform your doctor if you are allergic to any medicines.
Q. Can the use of Penom Clav 125mg/125mg Injection cause contraceptive failure?
Yes, the use of Penom Clav 125mg/125mg Injection can lower the efficacy of birth control pills. Consult your doctor and seek advice regarding the use of other methods of contraception (e.g., condom, diaphragm, spermicide) while you are taking Penom Clav 125mg/125mg Injection.
Q. Can I take a higher than the recommended dose of Penom Clav 125mg/125mg Injection?
No, taking a higher than the recommended dose of Penom Clav 125mg/125mg Injection can increase the risks of side effects. Penom Clav 125mg/125mg Injection takes time to show its full effect and treat your infection. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.
Q. What are the instructions for the storage and disposal of Penom Clav 125mg/125mg Injection?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose off the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can Penom Clav 125mg/125mg Injection cause an allergic reaction?
Yes, Penom Clav 125mg/125mg Injection can cause an allergic reaction. It is considered to be harmful for patients with known allergy to penicillins. Get emergency medical help if you have any signs of allergic reaction like hives, difficulty breathing, or swelling of your face, lips, tongue or throat.
Q. Can the use of Penom Clav 125mg/125mg Injection cause diarrhea?
Yes, the use of Penom Clav 125mg/125mg Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. In addition to that, the medicine may affect the helpful bacteria in your stomach or intestine as well and cause diarrhea. In case you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less frequency of urination with dark colored and strong-smelling urine. Do not take any other medicine without consulting a doctor.
