Manufacturer: Ferring Pharmaceuticals
Salt Composition : Mesalazine(1gm)
Pentasa 1gm Suppository is only for rectal route and should not be taken orally. It must be use under the supervision of a doctor or healthcare professional. Stay in a lying position for at least 15 minutes after the insertion of suppositories. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.
The most common side effects of this medicine include rectal discomfort, rash, itching, and fever. If these symptoms bother you, do not go away or get worse, tell your doctor. There may be ways of reducing or preventing them.
Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. You may be asked for kidney and liver function tests before and after the treatment.
Pentasa 1gm Suppository is an aminosalicylate. It works directly on the site of inflammation (swelling) in the lower parts of large intestine (colon and rectum) to provide rapid relief from attacks of ulcerative colitis. It suppresses the production of chemical messengers (prostaglandins) that cause intestinal inflammation, thereby reducing ulceration, bleeding and painful symptoms.
Rectal forms of mesalazine deliver active drug directly to the rectum and left colon. Plasma concentrations of mesalazine and its metabolite acetyl-5-aminosalicylic acid after oral or local administration are the result of systemic absorption and hepatic metabolism by N-acetyltransferase.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pentasa
Rectal discomfort
Flatulence
Headache
Vomiting
Diarrhea
Nausea
Abdominal pain
Rash
Contraindicated in patients with hypersensitivity to salicylates or to any of the components, and in severe renal impairment. Serious blood dyscrasias have been reported very rarely with mesalazine. Contraindicated in severe hepatic impairment.
Pentasa 1gm Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
No interaction found/established
Pentasa 1gm Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If you are taking Pentasa 1gm Suppository, monitor the baby for diarrhea.
Mesalazine is used to treat ulcerative colitis and Crohn's disease and other types of inflammatory bowel disease. It belongs to a group of medicines called aminosalicylates. These help to reduce redness and swelling (inflammation) and can help with healing. Some people take mesalazine together with steroids.
Drug-Drug Interactions: Inform your doctor if you are taking non-steroidal anti-inflammatory drugs (aspirin, ibuprofen), immunosuppressants (azathioprine) or other medicines.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: If you have kidney impairment, please inform your doctor before using the MESALAZINE.
Drug-Drug Interactions Checker List:
ASPIRIN
IBUPROFEN
AZATHIOPRINE
Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Store below 25°C
If you miss a dose of Pentasa 1gm Suppository, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Pentasa 1gm Suppository for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
It is for administration into the back passage (rectum). It must not be taken by mouth.
Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
Do not use Pentasa 1gm Suppository if you are allergic to aspirin or if you have blood disorders.
Do not stop using the medication suddenly without talking to your doctor.
Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.
Q. My symptoms have improved can I stop using Pentasa 1gm Suppository?
Continue to use Pentasa 1gm Suppository as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop using Pentasa 1gm Suppository without consulting your doctor.
Q. I am suffering from ulcerative colitis (UC) and piles can I use Pentasa 1gm Suppository?
Pentasa 1gm Suppository is used for the treatment of ulcerative colitis, however, you should not start using the medicine on your own. Consult a doctor who will prescribe you the right dose and duration of treatment and will address any related or other concerns that you have.
Q. Can I drink alcohol while using Pentasa 1gm Suppository?
You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Pentasa 1gm Suppository, you should consult your doctor before using alcohol.
Q. When is the best time to use Pentasa 1gm Suppository?
Use Pentasa 1gm Suppository exactly as directed by your doctor. If you are using Pentasa 1gm Suppository suppositories you should insert it rectally, once daily at bedtime.
